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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Western blot [2]
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- Product number
- MAB2378 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2378, RRID:AB_10677577
- Product name
- RNASEL monoclonal antibody, clone 2E9
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against full length recombinant RNASEL.
- Isotype
- IgG
- Antibody clone number
- 2E9
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L.
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1.
Elevated levels of 2',5'-linked oligoadenylate-dependent ribonuclease L occur as an early event in colorectal tumorigenesis.
2-5A-dependent RNase molecules dimerize during activation by 2-5A.
Han JQ, Townsend HL, Jha BK, Paranjape JM, Silverman RH, Barton DJ
Journal of virology 2007 Jun;81(11):5561-72
Journal of virology 2007 Jun;81(11):5561-72
Germline mutations in the ribonuclease L gene in families showing linkage with HPC1.
Carpten J, Nupponen N, Isaacs S, Sood R, Robbins C, Xu J, Faruque M, Moses T, Ewing C, Gillanders E, Hu P, Bujnovszky P, Makalowska I, Baffoe-Bonnie A, Faith D, Smith J, Stephan D, Wiley K, Brownstein M, Gildea D, Kelly B, Jenkins R, Hostetter G, Matikainen M, Schleutker J, Klinger K, Connors T, Xiang Y, Wang Z, De Marzo A, Papadopoulos N, Kallioniemi OP, Burk R, Meyers D, Grönberg H, Meltzer P, Silverman R, Bailey-Wilson J, Walsh P, Isaacs W, Trent J
Nature genetics 2002 Feb;30(2):181-4
Nature genetics 2002 Feb;30(2):181-4
Elevated levels of 2',5'-linked oligoadenylate-dependent ribonuclease L occur as an early event in colorectal tumorigenesis.
Wang L, Zhou A, Vasavada S, Dong B, Nie H, Church JM, Williams BR, Banerjee S, Silverman RH
Clinical cancer research : an official journal of the American Association for Cancer Research 1995 Nov;1(11):1421-8
Clinical cancer research : an official journal of the American Association for Cancer Research 1995 Nov;1(11):1421-8
2-5A-dependent RNase molecules dimerize during activation by 2-5A.
Dong B, Silverman RH
The Journal of biological chemistry 1995 Feb 24;270(8):4133-7
The Journal of biological chemistry 1995 Feb 24;270(8):4133-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of RNASEL in insect cell extracts transfected with recombinant human RNASEL using RNASEL monoclonal antibody, clone 2E9 (Cat # MAB2378).
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of RNASEL in transfected cells (0.1 ug) and Hey1B (100 ug), using RNASEL monoclonal antibody, clone 2E9 (Cat # MAB2378).
