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antibody from antibodies-online
Targeting: AURKA
AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7
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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [3]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393835 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Aurora Kinase A (AURKA) (AA 1-111) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-111
- Isotype
- IgG
- Antibody clone number
- 5F8
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Lack of an association between AURKA T91A polymorphisms and breast cancer: a meta-analysis involving 32,141 subjects.
Aurora kinase A as a rational target for therapy in glioblastoma.
Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase.
Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A.
Spindle proteins in resected pancreatic head adenocarcinomas: BubR1 is an independent prognostic factor in pancreatobiliary-type tumours.
Sun H, Bai J, Chen F, Jin Y, Yu Y, Fu S
Breast cancer research and treatment 2011 Jan;125(1):175-9
Breast cancer research and treatment 2011 Jan;125(1):175-9
Aurora kinase A as a rational target for therapy in glioblastoma.
Barton VN, Foreman NK, Donson AM, Birks DK, Handler MH, Vibhakar R
Journal of neurosurgery. Pediatrics 2010 Jul;6(1):98-105
Journal of neurosurgery. Pediatrics 2010 Jul;6(1):98-105
Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase.
Sánchez R, Pantoja-Uceda D, Prieto J, Diercks T, Marcaida MJ, Montoya G, Campos-Olivas R, Blanco FJ
The Journal of biological chemistry 2010 Jul 16;285(29):22196-201
The Journal of biological chemistry 2010 Jul 16;285(29):22196-201
Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A.
Molli PR, Li DQ, Bagheri-Yarmand R, Pakala SB, Katayama H, Sen S, Iyer J, Chernoff J, Tsai MY, Nair SS, Kumar R
The Journal of cell biology 2010 Jul 12;190(1):101-14
The Journal of cell biology 2010 Jul 12;190(1):101-14
Spindle proteins in resected pancreatic head adenocarcinomas: BubR1 is an independent prognostic factor in pancreatobiliary-type tumours.
Gladhaug IP, Westgaard A, Schjølberg AR, Burum-Auensen E, Pomianowska E, Clausen OP
Histopathology 2010 Feb;56(3):345-55
Histopathology 2010 Feb;56(3):345-55
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- WB
Supportive validation
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- ELISA
Supportive validation
- Submitted by
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- IHC
