abx001575

antibody from Abbexa

Targeting: BUB1 BUB1A, BUB1L, hBUB1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx001575

Provider

Abbexa

Product name

Mitotic Checkpoint Serine/threonine-Protein Kinase BUB1 (BUB1) Antibody

Antibody type

Polyclonal

Description

BUB1 Antibody is a Rabbit Polyclonal antibody against BUB1. This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

> 1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.