BS6340

antibody from Bioworld Technology, Inc
Targeting: CDK1 CDC2, CDC28A
Provider product page for BS6340
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6340 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Cdk1/Cdc2 (phospho T161) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human Cdk1/Cdc2 around the phosphorylation site of Serine 795.
Description
Cdc2, an evolutionarily conserved serine/threonine-specific protein kinase, is essential in the cell cycle transition from G2 to M phase. Cdc2 is regulated by association with B-type cyclins and by reversible phosophorylation. Cyclin B binding facilitates the phosphorylation of Cdc2 p34 on three regulatory sites: threonine 14, tyrosine 15, and threonine 161. In higher eukaryotes, Cdc2 is negatively regulated by phosphorylation of two residues located in the ATP-binding site, Thr 14 and Tyr 15. Cdc2 is positively regulated by the cyclin-dependent phosphorylation of Thr 161. Both phosphorylation and de- phosphorylation at Thr 161 are required for progression through the cell cycle.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CDK1 protein structure - BS6340 shown in red.