Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [4]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN393442 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 1-298) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-298
- Isotype
- IgG
- Antibody clone number
- 1A4-1A9
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Centrosome-related genes, genetic variation, and risk of breast cancer.
Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.
Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry.
Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis.
Olson JE, Wang X, Pankratz VS, Fredericksen ZS, Vachon CM, Vierkant RA, Cerhan JR, Couch FJ
Breast cancer research and treatment 2011 Jan;125(1):221-8
Breast cancer research and treatment 2011 Jan;125(1):221-8
Cdk1 activity is required for mitotic activation of aurora A during G2/M transition of human cells.
Van Horn RD, Chu S, Fan L, Yin T, Du J, Beckmann R, Mader M, Zhu G, Toth J, Blanchard K, Ye XS
The Journal of biological chemistry 2010 Jul 9;285(28):21849-57
The Journal of biological chemistry 2010 Jul 9;285(28):21849-57
Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.
Harley ME, Allan LA, Sanderson HS, Clarke PR
The EMBO journal 2010 Jul 21;29(14):2407-20
The EMBO journal 2010 Jul 21;29(14):2407-20
Phosphorylation of mixed lineage leukemia 5 by CDC2 affects its cellular distribution and is required for mitotic entry.
Liu J, Wang XN, Cheng F, Liou YC, Deng LW
The Journal of biological chemistry 2010 Jul 2;285(27):20904-14
The Journal of biological chemistry 2010 Jul 2;285(27):20904-14
Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis.
Gavet O, Pines J
Developmental cell 2010 Apr 20;18(4):533-43
Developmental cell 2010 Apr 20;18(4):533-43
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- WB
- Submitted by
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Supportive validation
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- antibodies-online (provider)
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- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
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- Experimental details
- IHC