H00051548-M01

antibody from Abnova Corporation

Targeting: SIRT6

ELISA (Supportive data in Antibodypedia)

Antibody Data

Product number

H00051548-M01

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#H00051548-M01, RRID:AB_1137449

Product name

SIRT6 monoclonal antibody (M01), clone 1D8

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against a partial recombinant SIRT6.

Antigen sequence

CAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLR
ACRGELRDTILDWEDSLPDRDLALADEASRNADLS
ITLGTSLQIRPSGNLPLATKRRGGRLVIVNLQPTK
HDRHA


Isotype

IgG

Antibody clone number

1D8

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References

Submitted references

SIRT6 expression is associated with poor prognosis and chemosensitivity in patients with non-small cell lung cancer.

Azuma Y, Yokobori T, Mogi A, Altan B, Yajima T, Kosaka T, Onozato R, Yamaki E, Asao T, Nishiyama M, Kuwano H
Journal of surgical oncology 2015 Aug;112(2):231-7

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Over expression of wild type or a catalytically dead mutant of Sirtuin 6 does not influence NFκB responses.

Grimley R, Polyakova O, Vamathevan J, McKenary J, Hayes B, Patel C, Smith J, Bridges A, Fosberry A, Bhardwaja A, Mouzon B, Chung CW, Barrett N, Richmond N, Modha S, Solari R
PloS one 2012;7(7):e39847

ELISA

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Detection limit for recombinant GST tagged SIRT6 is 1 ng/ml as a capture antibody.

Validation comment

Sandwich ELISA (Recombinant protein)

Protocol

Protocol