Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [3]
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Validation data
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- Product number
- MAB1050 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB1050, RRID:AB_1578982
- Product name
- PPM1A monoclonal antibody, clone p6c7
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against full length recombinant PPM1A.
- Isotype
- IgG
- Antibody clone number
- p6c7
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling.
Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway.
Lin X, Duan X, Liang YY, Su Y, Wrighton KH, Long J, Hu M, Davis CM, Wang J, Brunicardi FC, Shi Y, Chen YG, Meng A, Feng XH
Cell 2006 Jun 2;125(5):915-28
Cell 2006 Jun 2;125(5):915-28
Protein serine/threonine phosphatase PPM1A dephosphorylates Smad1 in the bone morphogenetic protein signaling pathway.
Duan X, Liang YY, Feng XH, Lin X
The Journal of biological chemistry 2006 Dec 1;281(48):36526-32
The Journal of biological chemistry 2006 Dec 1;281(48):36526-32
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunoblot analysis of mouse liver cytosol extract was resolved by electrophoresis , transferred to PVDF membrane and probed with PPM1A monoclonal antibody , clone p6c7 (1 : 250) (Cat # MAB1050) . Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicates PPM1A (~ 43 kDa) .
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- PPM1A monoclonal antibody, clone p6c7. Western blot analysis of PPM1 expression in Jurkat.
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- PPM1A monoclonal antibody, clone p6c7. Western blot analysis of PPM1 expression in human liver.