Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 18436-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18436-1-AP, RRID:AB_2171798
- Product name
- PRMT5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PRMT5 antibody (Cat. #18436-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Protein arginine methyltransferase 5 mediates THP-1-derived macrophage activation dependent on NF-κB in endometriosis.
Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response.
High PRMT5 expression is associated with poor overall survival and tumor progression in bladder cancer.
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Chai X, Wu X, He L, Ding H
Experimental and therapeutic medicine 2021 Sep;22(3):1003
Experimental and therapeutic medicine 2021 Sep;22(3):1003
Arginine methyltransferase PRMT5 negatively regulates cGAS-mediated antiviral immune response.
Ma D, Yang M, Wang Q, Sun C, Shi H, Jing W, Bi Y, Shen X, Ma X, Qin Z, Lin Y, Zhu L, Zhao Y, Cheng Y, Han L
Science advances 2021 Mar;7(13)
Science advances 2021 Mar;7(13)
High PRMT5 expression is associated with poor overall survival and tumor progression in bladder cancer.
Tan L, Xiao K, Ye Y, Liang H, Chen M, Luo J, Qin Z
Aging 2020 May 11;12(9):8728-8741
Aging 2020 May 11;12(9):8728-8741
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Li Z, Zhang J, Liu X, Li S, Wang Q, Di Chen, Hu Z, Yu T, Ding J, Li J, Yao M, Fan J, Huang S, Gao Q, Zhao Y, He X
Nature communications 2018 Apr 20;9(1):1572
Nature communications 2018 Apr 20;9(1):1572
USP9X regulates centrosome duplication and promotes breast carcinogenesis.
Li X, Song N, Liu L, Liu X, Ding X, Song X, Yang S, Shan L, Zhou X, Su D, Wang Y, Zhang Q, Cao C, Ma S, Yu N, Yang F, Wang Y, Yao Z, Shang Y, Shi L
Nature communications 2017 Mar 31;8:14866
Nature communications 2017 Mar 31;8:14866
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 18436-1-AP(PRMT5 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PRMT5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PRMT5. This antibody recognizes human,mouse,rat antigen. The PRMT5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.