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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Flow cytometry [1]
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- Product number
- MAB1207 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal IL-17RB Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human IL-17 RB in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant mouse (rm) IL-17 RB, recombinant human IL-17 R, or rmIL-17 R is observed.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs.
IL-17RB+ granulocytes are associated with airflow obstruction in asthma.
IL-25 in atopic dermatitis: a possible link between inflammation and skin barrier dysfunction?
Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts.
Bal SM, Bernink JH, Nagasawa M, Groot J, Shikhagaie MM, Golebski K, van Drunen CM, Lutter R, Jonkers RE, Hombrink P, Bruchard M, Villaudy J, Munneke JM, Fokkens W, Erjefält JS, Spits H, Ros XR
Nature immunology 2016 Jun;17(6):636-45
Nature immunology 2016 Jun;17(6):636-45
IL-17RB+ granulocytes are associated with airflow obstruction in asthma.
Li L, Lukacs NW, Schaller MA, Petersen B, Baptist AP
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2016 Dec;117(6):674-679
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2016 Dec;117(6):674-679
IL-25 in atopic dermatitis: a possible link between inflammation and skin barrier dysfunction?
Hvid M, Vestergaard C, Kemp K, Christensen GB, Deleuran B, Deleuran M
The Journal of investigative dermatology 2011 Jan;131(1):150-7
The Journal of investigative dermatology 2011 Jan;131(1):150-7
Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.
Islam SA, Chang DS, Colvin RA, Byrne MH, McCully ML, Moser B, Lira SA, Charo IF, Luster AD
Nature immunology 2011 Feb;12(2):167-77
Nature immunology 2011 Feb;12(2):167-77
IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts.
Létuvé S, Lajoie-Kadoch S, Audusseau S, Rothenberg ME, Fiset PO, Ludwig MS, Hamid Q
The Journal of allergy and clinical immunology 2006 Mar;117(3):590-6
The Journal of allergy and clinical immunology 2006 Mar;117(3):590-6
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of IL-17 RB in K562 Human Cell Line by Flow Cytometry. K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human IL-17 RB Monoclonal Antibody (Catalog # MAB1207, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).
