11-8080

antibody from ABEOMICS Inc.
Targeting: IPO7 Imp7, RANBP7
Provider product page for 11-8080

Antibody data

Product number
11-8080 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Importin 7 Antibody
Antibody type
Polyclonal
Description
Importin 7 (IPO7) is a soluble nuclear transport factor that is required for efficient import. It mediates transport of hTERT into the nucleus. Efficient transport also requires the cytoplasmic nucleoporin Nup358, which was previously implicated in nuclear import of a subset of proteins. Importin 7 plays an important role in nuclear protein import either by acting as autonomous nuclear transport receptor, or as an adapter like protein in association with the importin-beta subunit KPNB1. It serves itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant Import
in 7 protein (amino acids 1-322) wa
s used as the immunogen for this an
tibody.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
IPO7 protein structure - 11-8080 shown in red.