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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Product number
- BAF193 - Provider product page
- Provider
- R&D Systems
- Product name
- Human/Primate BCMA/TNFRSF17 Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human BCMA in ELISAs and Western blots. In sandwich ELISAs, less than 0.1% cross-reactivity with recombinant human (rh) APRIL, rhBAFF, rhTACI, and recombinant mouse BCMA is observed.
- Reactivity
- Human, Simian
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
Q6PE46- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references B-cell maturation antigen is a promising target for adoptive T-cell therapy of multiple myeloma.
Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo.
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells.
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells.
B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenstrom macroglobulinemia.
Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily.
Carpenter RO, Evbuomwan MO, Pittaluga S, Rose JJ, Raffeld M, Yang S, Gress RE, Hakim FT, Kochenderfer JN
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Apr 15;19(8):2048-60
Clinical cancer research : an official journal of the American Association for Cancer Research 2013 Apr 15;19(8):2048-60
Fusion toxin BLyS-gelonin inhibits growth of malignant human B cell lines in vitro and in vivo.
Luster TA, Mukherjee I, Carrell JA, Cho YH, Gill J, Kelly L, Garcia A, Ward C, Oh L, Ullrich SJ, Migone TS, Humphreys R
PloS one 2012;7(10):e47361
PloS one 2012;7(10):e47361
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells.
Ettinger R, Sims GP, Robbins R, Withers D, Fischer RT, Grammer AC, Kuchen S, Lipsky PE
Journal of immunology (Baltimore, Md. : 1950) 2007 Mar 1;178(5):2872-82
Journal of immunology (Baltimore, Md. : 1950) 2007 Mar 1;178(5):2872-82
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells.
Ettinger R, Sims GP, Robbins R, Withers D, Fischer RT, Grammer AC, Kuchen S, Lipsky PE
Journal of immunology (Baltimore, Md. : 1950) 2007 Mar 1;178(5):2872-82
Journal of immunology (Baltimore, Md. : 1950) 2007 Mar 1;178(5):2872-82
B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenstrom macroglobulinemia.
Elsawa SF, Novak AJ, Grote DM, Ziesmer SC, Witzig TE, Kyle RA, Dillon SR, Harder B, Gross JA, Ansell SM
Blood 2006 Apr 1;107(7):2882-8
Blood 2006 Apr 1;107(7):2882-8
Decreased survival of B cells of HIV-viremic patients mediated by altered expression of receptors of the TNF superfamily.
Moir S, Malaspina A, Pickeral OK, Donoghue ET, Vasquez J, Miller NJ, Krishnan SR, Planta MA, Turney JF, Justement JS, Kottilil S, Dybul M, Mican JM, Kovacs C, Chun TW, Birse CE, Fauci AS
The Journal of experimental medicine 2004 Oct 4;200(7):587-99
The Journal of experimental medicine 2004 Oct 4;200(7):587-99
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