BS1696

antibody from Bioworld Technology, Inc
Targeting: TGFBR2 MFS2, TBR-ii, TBRII
Provider product page for BS1696
Western blot
Immunohistochemistry

Antibody data

Product number
BS1696 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1696, RRID:AB_1663064
Product name
TGFÉÇ RII (E246) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 220-300 of Human TGFÉÇ RII.
Description
A total of three members of the TGFÉÇ family, TGFÉÇ1, TGFÉÇ2 and TGFÉÇ3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFÉÇs mediate their activity by high affinity binding to the type II receptor (TGFÉÇ RII) transmembrane protein with a cytoplasmic serine-threonine kinase domain. For signaling growth inhibition and early gene responses the type II receptor requires both its kinase activity and association with a TGFÉÇ-binding protein, designated the type I receptor. Two independent groups have recently described the cloning and sequence analysis of genes encoding TGFÉÇ type I receptor proteins designated ALK-5 (TÉÇR-1) and TSR-1, respectively.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TGFBR2 protein structure - BS1696 shown in red.