BS8108

antibody from Bioworld Technology, Inc
Targeting: M6PR CD-M6PR, CD-MPR
Provider product page for BS8108
Western blot
Immunohistochemistry

Antibody data

Product number
BS8108 - Provider product page
Provider
Bioworld Technology, Inc
Product name
M6PR polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human M6PR.
Description
CD-MPR (cation-dependent mannose-6-phosphate receptor) is an oligomeric transmembrane protein that plays a critical role in the intracellular delivery of phosphorylated lysosomal enzymes from the trans-Golgi network (TGN). Intracellular trafficking of CD-MPR is mediated by sorting signals in its 67 amino acid cytoplasmic tail, which prevent it from entering the lysosome, where it would be degraded. CD-MPR is predominantly expressed in mouse testicular germ cells and shows differentiated expression during maturation of rat spermatozoa. Increased expression of CD-MPR in Alzheimer£ªs disease and the location of the CD-MPR gene next to a region on chromosome 12 which is possibly linked to the disease indicate that CD-MPR may play a role in Alzheimer£ªs disease.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
M6PR protein structure - BS8108 shown in red.