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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- 16555-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SPG11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SPG11 antibody (Cat. #16555-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NUFIP1 is a ribosome receptor for starvation-induced ribophagy.
Loss of spatacsin function alters lysosomal lipid clearance leading to upper and lower motor neuron degeneration.
Lysosomal abnormalities in hereditary spastic paraplegia types SPG15 and SPG11.
Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.
A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system.
Wyant GA, Abu-Remaileh M, Frenkel EM, Laqtom NN, Dharamdasani V, Lewis CA, Chan SH, Heinze I, Ori A, Sabatini DM
Science (New York, N.Y.) 2018 May 18;360(6390):751-758
Science (New York, N.Y.) 2018 May 18;360(6390):751-758
Loss of spatacsin function alters lysosomal lipid clearance leading to upper and lower motor neuron degeneration.
Branchu J, Boutry M, Sourd L, Depp M, Leone C, Corriger A, Vallucci M, Esteves T, Matusiak R, Dumont M, Muriel MP, Santorelli FM, Brice A, El Hachimi KH, Stevanin G, Darios F
Neurobiology of disease 2017 Jun;102:21-37
Neurobiology of disease 2017 Jun;102:21-37
Lysosomal abnormalities in hereditary spastic paraplegia types SPG15 and SPG11.
Renvoisé B, Chang J, Singh R, Yonekawa S, FitzGibbon EJ, Mankodi A, Vanderver A, Schindler A, Toro C, Gahl WA, Mahuran DJ, Blackstone C, Pierson TM
Annals of clinical and translational neurology 2014 Jun 1;1(6):379-389
Annals of clinical and translational neurology 2014 Jun 1;1(6):379-389
Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.
Chang J, Lee S, Blackstone C
The Journal of clinical investigation 2014 Dec;124(12):5249-62
The Journal of clinical investigation 2014 Dec;124(12):5249-62
A hereditary spastic paraplegia mouse model supports a role of ZFYVE26/SPASTIZIN for the endolysosomal system.
Khundadze M, Kollmann K, Koch N, Biskup C, Nietzsche S, Zimmer G, Hennings JC, Huebner AK, Symmank J, Jahic A, Ilina EI, Karle K, Schöls L, Kessels M, Braulke T, Qualmann B, Kurth I, Beetz C, Hübner CA
PLoS genetics 2013;9(12):e1003988
PLoS genetics 2013;9(12):e1003988
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