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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- MAB2126 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CHL-1/L1CAM-2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CHL-1/L1CAM-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CHL-1 is observed.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
NP_006605- Isotype
- IgG
- Antibody clone number
- 316223
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.
Kim W, Ma L, Lomoio S, Willen R, Lombardo S, Dong J, Haydon PG, Tesco G
Molecular neurodegeneration 2018 Feb 2;13(1):6
Molecular neurodegeneration 2018 Feb 2;13(1):6
Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma.
Wolterink S, Moldenhauer G, Fogel M, Kiefel H, Pfeifer M, Lüttgau S, Gouveia R, Costa J, Endell J, Moebius U, Altevogt P
Cancer research 2010 Mar 15;70(6):2504-15
Cancer research 2010 Mar 15;70(6):2504-15
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