10-4048

antibody from ABEOMICS Inc.
Targeting: KLRB1 CD161, CLEC5B, hNKR-P1A, NKR, NKR-P1, NKR-P1A
Provider product page for 10-4048

Antibody data

Product number
10-4048 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-CD161 Antibody
Antibody type
Monoclonal
Description
CD161 is the human equivalent of mouse NK cell receptor P1A. It is a type II transmembrane glycoprotein with characteristics of the C-type lectin superfamily. The expression confines to lymphocytes found in human gut and liver, as well as blood, especially NK (natural killer) cells, Th17 (T helper 17) cells, and a population of unconventional T cells known as MAIT (mucosal-associated invariant T) cells. CD161 promotes T cell expansion and eventually has been identified as a marker of human IL-17-producing T cells. It plays a pivotal role in trans-endothelial migration and is also implicated in the pathogenesis of RA (rheumatoid arthritis) as well as graft-versus-host disease (GVHD).
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antigen sequence
A full length human CD161 protein w
as used as the immunogen for this a
ntibody.
Isotype
IgG
Antibody clone number
ABM2D74
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
KLRB1 protein structure - 10-4048 shown in red.