11-0949-42

antibody from Invitrogen Antibodies

Targeting: KLRD1 CD94

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

11-0949-42

Provider

Invitrogen Antibodies

Product name

CD94 Monoclonal Antibody (DX22), FITC, eBioscience™

Antibody type

Monoclonal

Antigen

Other

Description

Description: The DX22 monoclonal antibody reacts with human CD94, a 70 kDa type II transmembrane glycoprotein. CD94 belongs to the C-type lectin superfamily and is present as a heterodimer with NKG2 on the surface. CD94 is expressed by NK cells, a subset of gd T cells, and NKT cells and plays an important role in adhesion and activation of NK cell lineage.

Conjugate

Green dye

Antibody clone number

DX22

Concentration

5 µL/Test

References

Submitted references

Biological Therapy in Inflammatory Bowel Disease Patients Partly Restores Intestinal Innate Lymphoid Cell Subtype Equilibrium.

Creyns B, Jacobs I, Verstockt B, Cremer J, Ballet V, Vandecasteele R, Vanuytsel T, Ferrante M, Vermeire S, Van Assche G, Ceuppens JL, Breynaert C
Frontiers in immunology 2020;11:1847

---

CD62L Is a Functional and Phenotypic Marker for Circulating Innate Lymphoid Cell Precursors.

Bar-Ephraim YE, Koning JJ, Burniol Ruiz E, Konijn T, Mourits VP, Lakeman KA, Boon L, Bögels M, van Maanen JP, Den Haan JMM, van Egmond M, Bouma G, Reijmers RM, Mebius RE
Journal of immunology (Baltimore, Md. : 1950) 2019 Jan 1;202(1):171-182

---

Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation.

Cuff AO, Robertson FP, Stegmann KA, Pallett LJ, Maini MK, Davidson BR, Male V
Journal of immunology (Baltimore, Md. : 1950) 2016 Dec 1;197(11):4283-4291

---

Changes of cytokines during a spaceflight analog--a 45-day head-down bed rest.

Xu X, Tan C, Li P, Zhang S, Pang X, Liu H, Li L, Sun X, Zhang Y, Wu H, Chen X, Ge Q
PloS one 2013;8(10):e77401

---

Liver-resident NK cells confer adaptive immunity in skin-contact inflammation.

Peng H, Jiang X, Chen Y, Sojka DK, Wei H, Gao X, Sun R, Yokoyama WM, Tian Z
The Journal of clinical investigation 2013 Apr;123(4):1444-56

---

Neuron-interacting satellite glial cells in human trigeminal ganglia have an APC phenotype.

van Velzen M, Laman JD, Kleinjan A, Poot A, Osterhaus AD, Verjans GM
Journal of immunology (Baltimore, Md. : 1950) 2009 Aug 15;183(4):2456-61

---

Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits.

Lazetic S, Chang C, Houchins JP, Lanier LL, Phillips JH
Journal of immunology (Baltimore, Md. : 1950) 1996 Dec 1;157(11):4741-5

---

CD94 and a novel associated protein (94AP) form a NK cell receptor involved in the recognition of HLA-A, HLA-B, and HLA-C allotypes.

Phillips JH, Chang C, Mattson J, Gumperz JE, Parham P, Lanier LL
Immunity 1996 Aug;5(2):163-72

---

Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily.

Chang C, Rodríguez A, Carretero M, López-Botet M, Phillips JH, Lanier LL
European journal of immunology 1995 Sep;25(9):2433-7

Flow cytometry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Staining of normal human peripheral blood cells with staining buffer (autofluorescence) (dotted histogram) Anti-Human CD94 FITC (black histogram).

Conjugate

Green dye