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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB2988 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2988, RRID:AB_1574169
- Product name
- CUL4A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of CUL4A.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation.
WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor.
Huang J, Chen J
Oncogene 2008 Jul 3;27(29):4056-64
Oncogene 2008 Jul 3;27(29):4056-64
WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
Hu J, Zacharek S, He YJ, Lee H, Shumway S, Duronio RJ, Xiong Y
Genes & development 2008 Apr 1;22(7):866-71
Genes & development 2008 Apr 1;22(7):866-71
The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor.
Wen X, Duus KM, Friedrich TD, de Noronha CM
The Journal of biological chemistry 2007 Sep 14;282(37):27046-57
The Journal of biological chemistry 2007 Sep 14;282(37):27046-57
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of CUL4A (arrow) using rabbit CUL4A polyclonal antibody (Cat # PAB2988). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CUL4A gene (Lane 2) (Origene Technologies).
