Explore
Validate
Learn
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB10038 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB10038, RRID:AB_1672209
- Product name
- CUL4A polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of CUL4A.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.
CUL-4A is critical for early embryonic development.
Cullin 4A associates with the UV-damaged DNA-binding protein DDB.
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A.
Groisman R, Polanowska J, Kuraoka I, Sawada J, Saijo M, Drapkin R, Kisselev AF, Tanaka K, Nakatani Y
Cell 2003 May 2;113(3):357-67
Cell 2003 May 2;113(3):357-67
CUL-4A is critical for early embryonic development.
Li B, Ruiz JC, Chun KT
Molecular and cellular biology 2002 Jul;22(14):4997-5005
Molecular and cellular biology 2002 Jul;22(14):4997-5005
Cullin 4A associates with the UV-damaged DNA-binding protein DDB.
Shiyanov P, Nag A, Raychaudhuri P
The Journal of biological chemistry 1999 Dec 10;274(50):35309-12
The Journal of biological chemistry 1999 Dec 10;274(50):35309-12
ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Ohta T, Michel JJ, Schottelius AJ, Xiong Y
Molecular cell 1999 Apr;3(4):535-41
Molecular cell 1999 Apr;3(4):535-41
Human CUL-1, but not other cullin family members, selectively interacts with SKP1 to form a complex with SKP2 and cyclin A.
Michel JJ, Xiong Y
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Jun;9(6):435-49
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998 Jun;9(6):435-49
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical staining with CUL4A polyclonal antibody (Cat # PAB10038) was diluted 1 : 500 to detect CUL4 in human testis tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counter stain.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
