Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
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Validation data
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- Product number
- 14268-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ARNTL antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ARNTL antibody (Cat. #14268-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exogenous melatonin protects preimplantation embryo development from decabromodiphenyl ethane-induced circadian rhythm disorder and endogenous melatonin reduction.
Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.
REGγ regulates circadian clock by modulating BMAL1 protein stability.
Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation.
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Rev-erbα exacerbates hepatic steatosis in alcoholic liver diseases through regulating autophagy.
Involvement of Bmal1 and circadian clock signaling in chondrogenic differentiation of ATDC5 cells by fluoride.
MYC-Associated Factor MAX is a Regulator of the Circadian Clock.
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Circadian Clock Gene Bmal1 Regulates Bilirubin Detoxification: A Potential Mechanism of Feedback Control of Hyperbilirubinemia.
Pathophysiological significance of clock genes BMAL1 and PER2 as erythropoietin-controlling factors in acute blood hemorrhage.
ARNTL hypermethylation promotes tumorigenesis and inhibits cisplatin sensitivity by activating CDK5 transcription in nasopharyngeal carcinoma.
CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.
Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice.
Shi F, Qiu J, Zhang S, Zhao X, Feng D, Feng X
Environmental pollution (Barking, Essex : 1987) 2022 Jan 1;292(Pt B):118445
Environmental pollution (Barking, Essex : 1987) 2022 Jan 1;292(Pt B):118445
Suppression of DLBCL Progression by the E3 Ligase Trim35 Is Mediated by CLOCK Degradation and NK Cell Infiltration.
Tan X, Cao F, Tang F, Lu C, Yu Q, Feng S, Yang Z, Chen S, He X, He J, Weng L, Sun L
Journal of immunology research 2021;2021:9995869
Journal of immunology research 2021;2021:9995869
REGγ regulates circadian clock by modulating BMAL1 protein stability.
Kubra S, Zhang H, Si Y, Gao X, Wang T, Pan L, Li L, Zhong N, Fu J, Zhang B, Li X
Cell death discovery 2021 Nov 5;7(1):335
Cell death discovery 2021 Nov 5;7(1):335
Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation.
Jia M, Su B, Mo L, Qiu W, Ying J, Lin P, Yang B, Li D, Wang D, Xu L, Li H, Zhou Z, Li X, Li J
Oncology reports 2021 Mar;45(3):1033-1043
Oncology reports 2021 Mar;45(3):1033-1043
hPER3 promotes adipogenesis via hHSP90AA1-mediated inhibition of Notch1 pathway.
Wan X, Zhu L, Zhao L, Peng L, Xiong J, Yang W, Yuan J, Liang F, Zhang K, Chen K
Cell death & disease 2021 Mar 19;12(4):301
Cell death & disease 2021 Mar 19;12(4):301
Rev-erbα exacerbates hepatic steatosis in alcoholic liver diseases through regulating autophagy.
Liu Q, Xu L, Wu M, Zhou Y, Yang J, Huang C, Xu T, Li J, Zhang L
Cell & bioscience 2021 Jul 10;11(1):129
Cell & bioscience 2021 Jul 10;11(1):129
Involvement of Bmal1 and circadian clock signaling in chondrogenic differentiation of ATDC5 cells by fluoride.
Li D, Zhang R, Sun Q, Guo X
Ecotoxicology and environmental safety 2020 Nov;204:111058
Ecotoxicology and environmental safety 2020 Nov;204:111058
MYC-Associated Factor MAX is a Regulator of the Circadian Clock.
Blaževitš O, Bolshette N, Vecchio D, Guijarro A, Croci O, Campaner S, Grimaldi B
International journal of molecular sciences 2020 Mar 26;21(7)
International journal of molecular sciences 2020 Mar 26;21(7)
The tight junction protein TJP1 regulates the feeding-modulated hepatic circadian clock.
Liu Y, Zhang Y, Li T, Han J, Wang Y
Nature communications 2020 Jan 30;11(1):589
Nature communications 2020 Jan 30;11(1):589
Circadian Clock Gene Bmal1 Regulates Bilirubin Detoxification: A Potential Mechanism of Feedback Control of Hyperbilirubinemia.
Wang S, Lin Y, Zhou Z, Gao L, Yang Z, Li F, Wu B
Theranostics 2019;9(18):5122-5133
Theranostics 2019;9(18):5122-5133
Pathophysiological significance of clock genes BMAL1 and PER2 as erythropoietin-controlling factors in acute blood hemorrhage.
Tani N, Ikeda T, Aoki Y, Shida A, Oritani S, Ishikawa T
Human cell 2019 Jul;32(3):275-284
Human cell 2019 Jul;32(3):275-284
ARNTL hypermethylation promotes tumorigenesis and inhibits cisplatin sensitivity by activating CDK5 transcription in nasopharyngeal carcinoma.
Peng H, Zhang J, Zhang PP, Chen L, Tang LL, Yang XJ, He QM, Wen X, Sun Y, Liu N, Li YQ, Ma J
Journal of experimental & clinical cancer research : CR 2019 Jan 8;38(1):11
Journal of experimental & clinical cancer research : CR 2019 Jan 8;38(1):11
CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.
Lin R, Mo Y, Zha H, Qu Z, Xie P, Zhu ZJ, Xu Y, Xiong Y, Guan KL
Molecular cell 2017 Oct 5;68(1):198-209.e6
Molecular cell 2017 Oct 5;68(1):198-209.e6
Downregulation of the spinal dorsal horn clock gene Per1 expression leads to mechanical hypersensitivity via c-jun N-terminal kinase and CCL2 production in mice.
Morioka N, Saeki M, Sugimoto T, Higuchi T, Zhang FF, Nakamura Y, Hisaoka-Nakashima K, Nakata Y
Molecular and cellular neurosciences 2016 Apr;72:72-83
Molecular and cellular neurosciences 2016 Apr;72:72-83
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14268-1-AP( ARNTL Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ARNTL antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ARNTL. This antibody recognizes human,mouse,rat antigen. The ARNTL antibody has been validated for the following applications: ELISA, IP, WB analysis.