Ab102374

Targeting: ESR2 ER-beta, Erb, NR3A2

Western blot

Immunohistochemistry

Antibody data

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Validation data

Product number: Ab102374 - Provider product page
Provider: Aladdin Scientific Corporation
Product name: Estrogen Receptor beta Antibody
Antibody type: Polyclonal
Description: Rabbit anti Human Estrogen Receptor beta Antibody, Polyclonal, could be used for WB, IHC and so on.ApplicationWB: 1/500-1/1000IHC: 1/50-1/100Protein FunctionNuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 480-530
Vial size: 100μl,10μl,1ml,50μl
Concentration: 0,6 mg/ml
Storage: Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

ESR2 protein structure - Ab102374 shown in red.