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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- ELISA [1]
- Immunohistochemistry [1]
- Blocking/Neutralizing [1]
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- Product number
- AF664 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal LIGHT/TNFSF14 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human LIGHT/TNFSF14 in direct ELISAs and Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human (rh) APRIL is observed and less than 1% cross-reactivity with rhFas Ligand, rhTRAIL, and rhTNF-alpha is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Licensed human natural killer cells aid dendritic cell maturation via TNFSF14/LIGHT.
VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain.
Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes.
Holmes TD, Wilson EB, Black EV, Benest AV, Vaz C, Tan B, Tanavde VM, Cook GP
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 30;111(52):E5688-96
Proceedings of the National Academy of Sciences of the United States of America 2014 Dec 30;111(52):E5688-96
VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain.
Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Bréant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL
Nature neuroscience 2006 Mar;9(3):340-8
Nature neuroscience 2006 Mar;9(3):340-8
Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes.
Otterdal K, Smith C, Oie E, Pedersen TM, Yndestad A, Stang E, Endresen K, Solum NO, Aukrust P, Damås JK
Blood 2006 Aug 1;108(3):928-35
Blood 2006 Aug 1;108(3):928-35
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Human LIGHT/TNFSF14 ELISA Standard Curve. Human LIGHT/TNFSF14 ELISA Standard Curve.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- LIGHT/TNFSF14 in Human Spleen. LIGHT/TNFSF14 in Human Spleen.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Cell Proliferation Induced by LIGHT/TNFSF14 and Neutral-ization by Human LIGHT/ TNFSF14 Antibody. Cell Proliferation Induced by LIGHT/TNFSF14 and Neutral-ization by Human LIGHT/ TNFSF14 Antibody.
