Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS61000 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- TNFSF14 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human TNFSF14.
- Description
- Herpes virus entry mediator (HVEM), a type I transmembrane protein, is a member of the TNF receptor superfamily. HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD). HVEM also binds two cellular ligands, secreted lymphotoxin Ï« and light. LIGHT is a member of the TNF superfamily produced by activated T cells. This type II transmembrane protein competes with HSV glycoprotein D for binding to HVEM. LIGHT is closely related in sequence to lymphotoxin ÉÇ (LTÉÇ) and can also bind to the LTÉÇ receptor. LIGHT is also known to induce apoptosis and suppress tumor formation.The gene encoding LIGHT maps to human chromosome 19p13.3.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of TNFSF14 pAb at 1:500Line1:Hela whole cell lysateLine2:Raw264.7 whole cell lysate