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Learn25465-1-AP
antibody from Proteintech Group
Targeting: TWIST1
ACS3, bHLHa38, BPES2, BPES3, CRS, CRS1, H-twist, SCS, TWIST
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- Antigen structure
- References [98]
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- Product number
- 25465-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- TWIST1-specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TWIST1-specific antibody (Cat. #25465-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Epigenetic Repression of Chloride Channel Accessory 2 Transcription in Cardiac Fibroblast: Implication in Cardiac Fibrosis.
LncRNA UCID Promotes Hepatocellular Carcinoma Metastasis via Stabilization of Snail.
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1α/ TGF-β.
Inhibitory Effect of Dihydroartemisinin on the Proliferation and Migration of Melanoma Cells and Experimental Lung Metastasis From Melanoma in Mice.
Evaluating the Causal Association Between Educational Attainment and Asthma Using a Mendelian Randomization Design.
PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validation.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells.
Activation of activin/Smad2 and 3 signaling pathway and the potential involvement of endothelial‑mesenchymal transition in the valvular damage due to rheumatic heart disease.
The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis.
Inhibitory role of ATF3 in gastric cancer progression through regulating cell EMT and stemness.
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
Hsa_circ_0030586 promotes epithelial-mesenchymal transition in prostate cancer via PI3K-AKT signaling.
Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics.
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
Ajuba transactivates N-cadherin expression in colorectal cancer cells through interaction with Twist.
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression.
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
NF-κB/TWIST1 Mediates Migration and Phagocytosis of Macrophages in the Mice Model of Implant-Associated Staphylococcus aureus Osteomyelitis.
LMP1 promotes nasopharyngeal carcinoma metastasis through NTRK2-mediated anoikis resistance.
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis.
Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation.
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.
Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.
Polarization and function of tumor-associated macrophages mediate graphene oxide-induced photothermal cancer therapy.
MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway.
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
MiR-496 promotes migration and epithelial-mesenchymal transition by targeting RASSF6 in colorectal cancer.
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
Human Papillomavirus 16 (HPV16) E2 Repression of TWIST1 Transcription Is a Potential Mediator of HPV16 Cancer Outcomes.
Long non-coding RNA PHACTR2-AS1 promotes tongue squamous cell carcinoma metastasis by regulating Snail.
MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma.
Endosulfan triggers epithelial-mesenchymal transition via PTP4A3-mediated TGF-β signaling pathway in prostate cancer cells.
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis.
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
KIAA0101 is a novel transcriptional target of FoxM1 and is involved in the regulation of hepatocellular carcinoma microvascular invasion by regulating epithelial-mesenchymal transition.
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
The long noncoding RNA HOTTIP promotes breast cancer cell migration, invasiveness, and epithelial-mesenchymal transition via the Wnt-β-catenin signaling pathway.
CD36 promotes the epithelial-mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β.
Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition.
Zinc promotes prostate cancer cell chemosensitivity to paclitaxel by inhibiting epithelial-mesenchymal transition and inducing apoptosis.
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
miR-27a promotes endothelial-mesenchymal transition in hypoxia-induced pulmonary arterial hypertension by suppressing BMP signaling.
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.
Comparison of phenotypic markers and neural differentiation potential of human bone marrow stromal cells from the cranial bone and iliac crest.
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer.
LncRNA AFAP1-AS1 promotes tumorigenesis and epithelial-mesenchymal transition of osteosarcoma through RhoC/ROCK1/p38MAPK/Twist1 signaling pathway.
MKL1 overexpression predicts poor prognosis in patients with papillary thyroid cancer and promotes nodal metastasis.
Vps4A mediates the localization and exosome release of β-catenin to inhibit epithelial-mesenchymal transition in hepatocellular carcinoma.
Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines.
ACOT12-Dependent Alteration of Acetyl-CoA Drives Hepatocellular Carcinoma Metastasis by Epigenetic Induction of Epithelial-Mesenchymal Transition.
miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer.
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.
Deficiency of protein-L-isoaspartate (D-aspartate) O-methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma.
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy.
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
GATA4 is upregulated in nasopharyngeal cancer and facilitates epithelial-mesenchymal transition and metastasis through regulation of SLUG.
RhoJ promotes hypoxia induced endothelial-to-mesenchymal transition by activating WDR5 expression.
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
The distinct clinical features of giant cell tumor of bone in pagetic and non-pagetic patients are associated with genetic, biochemical and histological differences.
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
In vitro anticancer activities of osthole against renal cell carcinoma cells.
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
HMGA2 regulates epithelial-mesenchymal transition and the acquisition of tumor stem cell properties through TWIST1 in gastric cancer.
CDH11 inhibits proliferation and invasion in head and neck cancer.
AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition.
Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling.
Shao T, Xue Y, Fang M
Frontiers in cell and developmental biology 2021;9:771466
Frontiers in cell and developmental biology 2021;9:771466
LncRNA UCID Promotes Hepatocellular Carcinoma Metastasis via Stabilization of Snail.
Yuan S, Si W, Zhuang K, Li Y, Zhang Y, Liu J, Yang L, Zhang X
OncoTargets and therapy 2021;14:725-736
OncoTargets and therapy 2021;14:725-736
Nogo-B receptor is required for stabilizing TGF-β type I receptor and promotes the TGF-β1-induced epithelial-to-mesenchymal transition of non-small cell lung cancer.
Wu D, Zhao B, Song Y, Chi X, Fu H, Guan T, Zhang L, Yang X, Hu K, Huang R, Jin X, Miao QR, Shao S
Journal of Cancer 2021;12(3):717-725
Journal of Cancer 2021;12(3):717-725
Dextran Sulfate Effects EMT of Human Gastric Cancer Cells by Reducing HIF-1α/ TGF-β.
Huang YN, Xu YY, Ma Q, Li MQ, Guo JX, Wang X, Jin X, Shang J, Jiao LX
Journal of Cancer 2021;12(11):3367-3377
Journal of Cancer 2021;12(11):3367-3377
Inhibitory Effect of Dihydroartemisinin on the Proliferation and Migration of Melanoma Cells and Experimental Lung Metastasis From Melanoma in Mice.
Zhang Q, Jin L, Jin Q, Wei Q, Sun M, Yue Q, Liu H, Li F, Li H, Ren X, Jin G
Frontiers in pharmacology 2021;12:727275
Frontiers in pharmacology 2021;12:727275
Evaluating the Causal Association Between Educational Attainment and Asthma Using a Mendelian Randomization Design.
Li Y, Chen W, Tian S, Xia S, Yang B
Frontiers in genetics 2021;12:716364
Frontiers in genetics 2021;12:716364
PLAU Promotes Cell Proliferation and Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma.
Chen G, Sun J, Xie M, Yu S, Tang Q, Chen L
Frontiers in genetics 2021;12:651882
Frontiers in genetics 2021;12:651882
TRIM50 Suppresses Pancreatic Cancer Progression and Reverses the Epithelial-Mesenchymal Transition via Facilitating the Ubiquitous Degradation of Snail1.
Li R, Zhu L, Peng Y, Zhang X, Dai C, Liu D
Frontiers in oncology 2021;11:695740
Frontiers in oncology 2021;11:695740
Transcription factor POU4F2 promotes colorectal cancer cell migration and invasion through hedgehog-mediated epithelial-mesenchymal transition.
Guo K, Wang P, Zhang L, Zhou Y, Dai X, Yan Y, Chen Y, Wasan HS, Yu J, Ruan S, Sun L
Cancer science 2021 Oct;112(10):4176-4186
Cancer science 2021 Oct;112(10):4176-4186
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validation.
Song F, Zhang Y, Pan Z, Hu X, Yi Y, Zheng X, Wei H, Huang P
Cancer cell international 2021 Oct 25;21(1):559
Cancer cell international 2021 Oct 25;21(1):559
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma.
Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X
Clinical and translational medicine 2021 Mar;11(3):e337
Clinical and translational medicine 2021 Mar;11(3):e337
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
Zhang J, Yan L, Wei P, Zhou R, Hua C, Xiao M, Tu Y, Gu Z, Wei T
European journal of pharmacology 2021 Mar 15;895:173866
European journal of pharmacology 2021 Mar 15;895:173866
Overexpression of SERPINA3 promotes tumor invasion and migration, epithelial-mesenchymal-transition in triple-negative breast cancer cells.
Zhang Y, Tian J, Qu C, Peng Y, Lei J, Li K, Zong B, Sun L, Liu S
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):859-873
Breast cancer (Tokyo, Japan) 2021 Jul;28(4):859-873
Activation of activin/Smad2 and 3 signaling pathway and the potential involvement of endothelial‑mesenchymal transition in the valvular damage due to rheumatic heart disease.
Xian S, Chen A, Wu X, Lu C, Wu Y, Huang F, Zeng Z
Molecular medicine reports 2021 Jan;23(1)
Molecular medicine reports 2021 Jan;23(1)
The long intergenic noncoding RNA GAS5 reduces cisplatin-resistance in non-small cell lung cancer through the miR-217/LHPP axis.
Yang X, Meng L, Zhong Y, Hu F, Wang L, Wang M
Aging 2021 Jan 8;13(2):2864-2884
Aging 2021 Jan 8;13(2):2864-2884
Inhibitory role of ATF3 in gastric cancer progression through regulating cell EMT and stemness.
Huang C, Chen R, Zheng F, Tang Y, Wang X, Chen Z, Lai X
Cancer cell international 2021 Feb 19;21(1):127
Cancer cell international 2021 Feb 19;21(1):127
Knockdown of METTL14 suppresses the malignant progression of non-small cell lung cancer by reducing Twist expression.
Yang F, Yuan WQ, Li J, Luo YQ
Oncology letters 2021 Dec;22(6):847
Oncology letters 2021 Dec;22(6):847
Hsa_circ_0030586 promotes epithelial-mesenchymal transition in prostate cancer via PI3K-AKT signaling.
Luo GC, Chen L, Fang J, Yan ZJ
Bioengineered 2021 Dec;12(2):11089-11107
Bioengineered 2021 Dec;12(2):11089-11107
Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics.
Ding FP, Tian JY, Wu J, Han DF, Zhao D
Cancer cell international 2021 Dec 2;21(1):640
Cancer cell international 2021 Dec 2;21(1):640
Chromium (VI) promotes EMT by regulating FLNA in BLCA.
Sheng F, Chen KX, Liu J, Li JX, Liang GH, Xu Y, Du E, Zhang ZH
Environmental toxicology 2021 Aug;36(8):1694-1701
Environmental toxicology 2021 Aug;36(8):1694-1701
Ajuba transactivates N-cadherin expression in colorectal cancer cells through interaction with Twist.
Wu Z, Zou X, Xu Y, Zhou F, Kuai R, Li J, Yang D, Chu Y, Peng H
Journal of cellular and molecular medicine 2021 Aug;25(16):8006-8014
Journal of cellular and molecular medicine 2021 Aug;25(16):8006-8014
Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway.
Tao M, Zheng D, Liang X, Wu D, Hu K, Jin J, He Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression.
Miao L, Zhuo Z, Tang J, Huang X, Liu J, Wang HY, Xia H, He J
Clinical and translational medicine 2021 Apr;11(4):e395
Clinical and translational medicine 2021 Apr;11(4):e395
Paeoniflorin Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension by Inhibiting Endothelial-to-Mesenchymal Transition.
Yu M, Peng L, Liu P, Yang M, Zhou H, Ding Y, Wang J, Huang W, Tan Q, Wang Y, Xie W, Kong H, Wang H
Drug design, development and therapy 2020;14:1191-1202
Drug design, development and therapy 2020;14:1191-1202
Inhibiting EMT, stemness and cell cycle involved in baicalin-induced growth inhibition and apoptosis in colorectal cancer cells.
Yang B, Bai H, Sa Y, Zhu P, Liu P
Journal of Cancer 2020;11(8):2303-2317
Journal of Cancer 2020;11(8):2303-2317
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
Huang J, Tong X, Zhang L, Zhang Y, Wang L, Wang D, Zhang S, Fan H
Frontiers in pharmacology 2020;11:550955
Frontiers in pharmacology 2020;11:550955
NF-κB/TWIST1 Mediates Migration and Phagocytosis of Macrophages in the Mice Model of Implant-Associated Staphylococcus aureus Osteomyelitis.
Wang Y, Lin Y, Cheng C, Chen P, Zhang P, Wu H, Li K, Deng Y, Qian J, Zhang X, Yu B
Frontiers in microbiology 2020;11:1301
Frontiers in microbiology 2020;11:1301
LMP1 promotes nasopharyngeal carcinoma metastasis through NTRK2-mediated anoikis resistance.
Li Z, Zhou Z, Wu X, Zhou Q, Liao C, Liu Y, Li D, Shen L, Feng D, Yang L
American journal of cancer research 2020;10(7):2083-2099
American journal of cancer research 2020;10(7):2083-2099
FAM83A Promotes Lung Cancer Progression by Regulating the Wnt and Hippo Signaling Pathways and Indicates Poor Prognosis.
Zheng YW, Li ZH, Lei L, Liu CC, Wang Z, Fei LR, Yang MQ, Huang WJ, Xu HT
Frontiers in oncology 2020;10:180
Frontiers in oncology 2020;10:180
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol (SQ) inhibits cancer cell metastasis behavior of TNBC via suppressing EMT and VEGF.
Zheng D, Wu Z, Han J, Guan Q, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 Sep 25;329:109202
Chemico-biological interactions 2020 Sep 25;329:109202
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438
Oncology research 2020 Sep 1;28(4):423-438
MYCT1 inhibits the EMT and migration of laryngeal cancer cells via the SP1/miR-629-3p/ESRP2 pathway.
Yue PJ, Sun YY, Li YH, Xu ZM, Fu WN
Cellular signalling 2020 Oct;74:109709
Cellular signalling 2020 Oct;74:109709
A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis.
Li L, Pan Y, Mo X, Wei T, Song J, Luo M, Huang G, Teng C, Liang K, Mao N, Yang J
Journal of cancer research and clinical oncology 2020 Oct;146(10):2519-2534
Journal of cancer research and clinical oncology 2020 Oct;146(10):2519-2534
Calcium Channel Blocker Nifedipine Suppresses Colorectal Cancer Progression and Immune Escape by Preventing NFAT2 Nuclear Translocation.
Wu L, Lin W, Liao Q, Wang H, Lin C, Tang L, Lian W, Chen Z, Li K, Xu L, Zhou R, Ding Y, Zhao L
Cell reports 2020 Oct 27;33(4):108327
Cell reports 2020 Oct 27;33(4):108327
Polydatin executes anticancer effects against glioblastoma multiforme by inhibiting the EGFR-AKT/ERK1/2/STAT3-SOX2/Snail signaling pathway.
Chen Y, Niu J, Li L, Li Z, Jiang J, Zhu M, Dong T, Zhang J, Shi C, Xu P, Lu Y, Jiang Y, Liu P, Chen W
Life sciences 2020 Oct 1;258:118158
Life sciences 2020 Oct 1;258:118158
Wnt/β-Catenin Signaling Axis Is Required for TFEB-Mediated Gastric Cancer Metastasis and Epithelial-Mesenchymal Transition.
Li S, Liu F, Xu L, Li C, Yang X, Guo B, Gu J, Wang L
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
Molecular cancer research : MCR 2020 Nov;18(11):1650-1659
MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells.
Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, Li Z, Zuo D, Zhang W, Wu Y
Chemico-biological interactions 2020 May 25;323:109074
Chemico-biological interactions 2020 May 25;323:109074
Cyclovirobuxine D Exerts Anticancer Effects by Suppressing the EGFR-FAK-AKT/ERK1/2-Slug Signaling Pathway in Human Hepatocellular Carcinoma.
Zhang J, Chen Y, Lin J, Jia R, An T, Dong T, Zhang Y, Yang X
DNA and cell biology 2020 Mar;39(3):355-367
DNA and cell biology 2020 Mar;39(3):355-367
(20S)G-Rh2 Inhibits NF-κB Regulated Epithelial-Mesenchymal Transition by Targeting Annexin A2.
Wang YS, Li H, Li Y, Zhang S, Jin YH
Biomolecules 2020 Mar 31;10(4)
Biomolecules 2020 Mar 31;10(4)
Upregulated NTF4 in colorectal cancer promotes tumor development via regulating autophagy.
Yang Z, Chen Y, Wei X, Wu D, Min Z, Quan Y
International journal of oncology 2020 Jun;56(6):1442-1454
International journal of oncology 2020 Jun;56(6):1442-1454
Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial-mesenchymal transition through the TGF-β/Smad pathway.
Liu J, Chen Y, Cao Z, Guan B, Peng J, Chen Y, Zhan Z, Sferra TJ, Sankararaman S, Lin J
The Journal of international medical research 2020 Jun;48(6):300060520925598
The Journal of international medical research 2020 Jun;48(6):300060520925598
Polarization and function of tumor-associated macrophages mediate graphene oxide-induced photothermal cancer therapy.
Deng X, Liang H, Yang W, Shao Z
Journal of photochemistry and photobiology. B, Biology 2020 Jul;208:111913
Journal of photochemistry and photobiology. B, Biology 2020 Jul;208:111913
MicroRNA-29b-3p suppresses oral squamous cell carcinoma cell migration and invasion via IL32/AKT signalling pathway.
He J, Ye W, Kou N, Chen K, Cui B, Zhang X, Hu S, Liu T, Kang L, Li X
Journal of cellular and molecular medicine 2020 Jan;24(1):841-849
Journal of cellular and molecular medicine 2020 Jan;24(1):841-849
Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis.
Zheng Y, Nie P, Xu S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jan;121:109628
MiR-496 promotes migration and epithelial-mesenchymal transition by targeting RASSF6 in colorectal cancer.
Wang H, Yan B, Zhang P, Liu S, Li Q, Yang J, Yang F, Chen E
Journal of cellular physiology 2020 Feb;235(2):1469-1479
Journal of cellular physiology 2020 Feb;235(2):1469-1479
Capping Protein Regulator and Myosin 1 Linker 3 Is Required for Tumor Metastasis.
Wang H, Wang C, Peng G, Yu D, Cui XG, Sun YH, Ma X
Molecular cancer research : MCR 2020 Feb;18(2):240-252
Molecular cancer research : MCR 2020 Feb;18(2):240-252
Human Papillomavirus 16 (HPV16) E2 Repression of TWIST1 Transcription Is a Potential Mediator of HPV16 Cancer Outcomes.
Fontan CT, Das D, Bristol ML, James CD, Wang X, Lohner H, Atfi A, Morgan IM
mSphere 2020 Dec 9;5(6)
mSphere 2020 Dec 9;5(6)
Long non-coding RNA PHACTR2-AS1 promotes tongue squamous cell carcinoma metastasis by regulating Snail.
Yuan F, Miao Z, Chen W, Wu F, Wei C, Yong J, Xiao C
Journal of biochemistry 2020 Dec 26;168(6):651-657
Journal of biochemistry 2020 Dec 26;168(6):651-657
MELK is an oncogenic kinase essential for metastasis, mitotic progression, and programmed death in lung carcinoma.
Tang Q, Li W, Zheng X, Ren L, Liu J, Li S, Wang J, Du G
Signal transduction and targeted therapy 2020 Dec 2;5(1):279
Signal transduction and targeted therapy 2020 Dec 2;5(1):279
Endosulfan triggers epithelial-mesenchymal transition via PTP4A3-mediated TGF-β signaling pathway in prostate cancer cells.
Wang Y, Guo Y, Hu Y, Sun Y, Xu D
The Science of the total environment 2020 Aug 20;731:139234
The Science of the total environment 2020 Aug 20;731:139234
Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model.
Guo Y, Fan Y, Pei X
Cancer medicine 2020 Apr;9(7):2564-2578
Cancer medicine 2020 Apr;9(7):2564-2578
Wu-Mei-Wan ameliorates chronic colitis-associated intestinal fibrosis through inhibiting fibroblast activation.
Wu F, Shao Q, Hu M, Zhao Y, Dong R, Fang K, Xu L, Zou X, Lu F, Li J, Chen G
Journal of ethnopharmacology 2020 Apr 24;252:112580
Journal of ethnopharmacology 2020 Apr 24;252:112580
Mitochondrial oxidative stress by Lon-PYCR1 maintains an immunosuppressive tumor microenvironment that promotes cancer progression and metastasis.
Kuo CL, Chou HY, Chiu YC, Cheng AN, Fan CC, Chang YN, Chen CH, Jiang SS, Chen NJ, Lee AY
Cancer letters 2020 Apr 1;474:138-150
Cancer letters 2020 Apr 1;474:138-150
Oncogenic MSH6-CXCR4-TGFB1 Feedback Loop: A Novel Therapeutic Target of Photothermal Therapy in Glioblastoma Multiforme.
Chen Y, Liu P, Sun P, Jiang J, Zhu Y, Dong T, Cui Y, Tian Y, An T, Zhang J, Li Z, Yang X
Theranostics 2019;9(5):1453-1473
Theranostics 2019;9(5):1453-1473
2-Methoxy-5((3,4,5-trimethosyphenyl)seleninyl) phenol reverses EGF-induced cell migration and invasion through down-regulation of MDM2 in breast cancer cell lines.
Zheng D, Chang X, Liu Y, Xu J, Gou W, Li Z, Zuo D, Zhang W, Wu Y
Cancer biology & therapy 2019;20(4):513-523
Cancer biology & therapy 2019;20(4):513-523
SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial-mesenchymal transition.
Yang Z, Yu W, Huang R, Ye M, Min Z
Cancer cell international 2019;19:17
Cancer cell international 2019;19:17
Exosomal Tenascin-c induces proliferation and invasion of pancreatic cancer cells by WNT signaling.
Qian S, Tan X, Liu X, Liu P, Wu Y
OncoTargets and therapy 2019;12:3197-3205
OncoTargets and therapy 2019;12:3197-3205
Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1.
Liu K, Du S, Gao P, Zheng J
Journal of Cancer 2019;10(18):4196-4207
Journal of Cancer 2019;10(18):4196-4207
KIAA0101 is a novel transcriptional target of FoxM1 and is involved in the regulation of hepatocellular carcinoma microvascular invasion by regulating epithelial-mesenchymal transition.
Zhang T, Guo J, Gu J, Chen K, Wang Z, Li H, Wang G, Wang J
Journal of Cancer 2019;10(15):3501-3516
Journal of Cancer 2019;10(15):3501-3516
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Wei C, Zhang R, Cai Q, Gao X, Tong F, Dong J, Hu Y, Wu G, Dong X
Aging 2019 Sep 8;11(17):6734-6761
Aging 2019 Sep 8;11(17):6734-6761
The long noncoding RNA HOTTIP promotes breast cancer cell migration, invasiveness, and epithelial-mesenchymal transition via the Wnt-β-catenin signaling pathway.
Han S, Jin X, Liu Z, Xing F, Han Y, Yu X, He G, Qiu F
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Oct;97(5):655-664
Biochemistry and cell biology = Biochimie et biologie cellulaire 2019 Oct;97(5):655-664
CD36 promotes the epithelial-mesenchymal transition and metastasis in cervical cancer by interacting with TGF-β.
Deng M, Cai X, Long L, Xie L, Ma H, Zhou Y, Liu S, Zeng C
Journal of translational medicine 2019 Oct 26;17(1):352
Journal of translational medicine 2019 Oct 26;17(1):352
Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition.
Wu Y, Chen K, Xing G, Li L, Ma B, Hu Z, Duan L, Liu X
Science advances 2019 Nov;5(11):eaax7525
Science advances 2019 Nov;5(11):eaax7525
Zinc promotes prostate cancer cell chemosensitivity to paclitaxel by inhibiting epithelial-mesenchymal transition and inducing apoptosis.
Xue YN, Yu BB, Liu YN, Guo R, Li JL, Zhang LC, Su J, Sun LK, Li Y
The Prostate 2019 May;79(6):647-656
The Prostate 2019 May;79(6):647-656
Upregulated forkhead-box A3 elevates the expression of forkhead-box A1 and forkhead-box A2 to promote metastasis in esophageal cancer.
Chen B, Yu J, Lu L, Dong F, Zhou F, Tao X, Sun E
Oncology letters 2019 May;17(5):4351-4360
Oncology letters 2019 May;17(5):4351-4360
Nuciferine inhibits the progression of glioblastoma by suppressing the SOX2-AKT/STAT3-Slug signaling pathway.
Li Z, Chen Y, An T, Liu P, Zhu J, Yang H, Zhang W, Dong T, Jiang J, Zhang Y, Jiang M, Yang X
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Journal of experimental & clinical cancer research : CR 2019 Mar 29;38(1):139
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability.
Shen Z, Liao X, Shao Z, Feng M, Yuan J, Wang S, Gan S, Ha Y, He Z, Jie W
BMC cancer 2019 Mar 22;19(1):262
BMC cancer 2019 Mar 22;19(1):262
miR-27a promotes endothelial-mesenchymal transition in hypoxia-induced pulmonary arterial hypertension by suppressing BMP signaling.
Liu T, Zou XZ, Huang N, Ge XY, Yao MZ, Liu H, Zhang Z, Hu CP
Life sciences 2019 Jun 15;227:64-73
Life sciences 2019 Jun 15;227:64-73
FOXC1 silencing inhibits the epithelial‑to‑mesenchymal transition of glioma cells: Involvement of β‑catenin signaling.
Cao Q, Wang X, Shi Y, Zhang M, Yang J, Dong M, Mi Y, Zhang Z, Liu K, Jiang L, Wang N, Wang P
Molecular medicine reports 2019 Jan;19(1):251-261
Molecular medicine reports 2019 Jan;19(1):251-261
Comparison of phenotypic markers and neural differentiation potential of human bone marrow stromal cells from the cranial bone and iliac crest.
Ma Y, Ma J, Zhao Y, Yang K, Zhou J, Gao F, Pan R, Lu G
Journal of cellular physiology 2019 Jan 24;
Journal of cellular physiology 2019 Jan 24;
BECN1 promotes the migration of NSCLC cells through regulating the ubiquitination of Vimentin.
Cheng Z, Xin H, Han T
Cell adhesion & migration 2019 Dec;13(1):249-259
Cell adhesion & migration 2019 Dec;13(1):249-259
CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer.
Yu S, Zhang Y, Li Q, Zhang Z, Zhao G, Xu J
Cell death & disease 2019 Dec 11;10(12):949
Cell death & disease 2019 Dec 11;10(12):949
LncRNA AFAP1-AS1 promotes tumorigenesis and epithelial-mesenchymal transition of osteosarcoma through RhoC/ROCK1/p38MAPK/Twist1 signaling pathway.
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Journal of experimental & clinical cancer research : CR 2019 Aug 23;38(1):375
Journal of experimental & clinical cancer research : CR 2019 Aug 23;38(1):375
MKL1 overexpression predicts poor prognosis in patients with papillary thyroid cancer and promotes nodal metastasis.
Cheng X, Xu S, Pan J, Zheng J, Wang X, Yu H, Bao J, Xu Y, Guan H, Zhang L
Journal of cell science 2019 Aug 22;132(16)
Journal of cell science 2019 Aug 22;132(16)
Vps4A mediates the localization and exosome release of β-catenin to inhibit epithelial-mesenchymal transition in hepatocellular carcinoma.
Han Q, Lv L, Wei J, Lei X, Lin H, Li G, Cao J, Xie J, Yang W, Wu S, You J, Lu J, Liu P, Min J
Cancer letters 2019 Aug 10;457:47-59
Cancer letters 2019 Aug 10;457:47-59
Effects of SIRT1 silencing on viability, invasion and metastasis of human glioma cell lines.
Li Y, Chen X, Cui Y, Wei Q, Chen S, Wang X
Oncology letters 2019 Apr;17(4):3701-3708
Oncology letters 2019 Apr;17(4):3701-3708
ACOT12-Dependent Alteration of Acetyl-CoA Drives Hepatocellular Carcinoma Metastasis by Epigenetic Induction of Epithelial-Mesenchymal Transition.
Lu M, Zhu WW, Wang X, Tang JJ, Zhang KL, Yu GY, Shao WQ, Lin ZF, Wang SH, Lu L, Zhou J, Wang LX, Jia HL, Dong QZ, Chen JH, Lu JQ, Qin LX
Cell metabolism 2019 Apr 2;29(4):886-900.e5
Cell metabolism 2019 Apr 2;29(4):886-900.e5
miR-26a/HOXC9 Dysregulation Promotes Metastasis and Stem Cell-Like Phenotype of Gastric Cancer.
Peng X, Kang Q, Wan R, Wang Z
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(4):1659-1676
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;49(4):1659-1676
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Bao Y, Zhang S, Guo Y, Wei X, Zhang Y, Yang Y, Zhang H, Ma M, Yang W
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis.
He T, Jin M, Xu C, Ma Z, Wu F, Zhang X
Oncogene 2018 Oct;37(43):5766-5779
Oncogene 2018 Oct;37(43):5766-5779
Deficiency of protein-L-isoaspartate (D-aspartate) O-methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma.
Yamashita M, Ogasawara M, Kawasaki Y, Niisato M, Saito H, Kasai S, Maesawa C, Maemondo M, Yamauchi K
Oncotarget 2018 Mar 2;9(17):13287-13300
Oncotarget 2018 Mar 2;9(17):13287-13300
Long Non-coding RNA LINC00339 Stimulates Glioma Vasculogenic Mimicry Formation by Regulating the miR-539-5p/TWIST1/MMPs Axis.
Guo J, Cai H, Liu X, Zheng J, Liu Y, Gong W, Chen J, Xi Z, Xue Y
Molecular therapy. Nucleic acids 2018 Mar 2;10:170-186
Molecular therapy. Nucleic acids 2018 Mar 2;10:170-186
Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy.
Shen T, Cai LD, Liu YH, Li S, Gan WJ, Li XM, Wang JR, Guo PD, Zhou Q, Lu XX, Sun LN, Li JM
Journal of hematology & oncology 2018 Jul 17;11(1):95
Journal of hematology & oncology 2018 Jul 17;11(1):95
Autophagy promotes fibrosis and apoptosis in the peritoneum during long-term peritoneal dialysis.
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Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
Journal of cellular and molecular medicine 2018 Feb;22(2):1190-1201
PIM1 mediates epithelial-mesenchymal transition by targeting Smads and c-Myc in the nucleus and potentiates clear-cell renal-cell carcinoma oncogenesis.
Zhao B, Liu L, Mao J, Zhang Z, Wang Q, Li Q
Cell death & disease 2018 Feb 22;9(3):307
Cell death & disease 2018 Feb 22;9(3):307
GATA4 is upregulated in nasopharyngeal cancer and facilitates epithelial-mesenchymal transition and metastasis through regulation of SLUG.
Zhou Y, Chang H, Yang B
Experimental and therapeutic medicine 2018 Dec;16(6):5318-5326
Experimental and therapeutic medicine 2018 Dec;16(6):5318-5326
RhoJ promotes hypoxia induced endothelial-to-mesenchymal transition by activating WDR5 expression.
Liu L, Chen J, Sun L, Xu Y
Journal of cellular biochemistry 2018 Apr;119(4):3384-3393
Journal of cellular biochemistry 2018 Apr;119(4):3384-3393
Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway.
Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, Miao QR, Shao S
Cancer letters 2018 Apr 1;418:135-146
Cancer letters 2018 Apr 1;418:135-146
The distinct clinical features of giant cell tumor of bone in pagetic and non-pagetic patients are associated with genetic, biochemical and histological differences.
Divisato G, Scotto di Carlo F, Pazzaglia L, Rizzo R, Coviello DA, Benassi MS, Picci P, Esposito T, Gianfrancesco F
Oncotarget 2017 Sep 8;8(38):63121-63131
Oncotarget 2017 Sep 8;8(38):63121-63131
TMEM17 depresses invasion and metastasis in lung cancer cells via ERK signaling pathway.
Zhang X, Zhang Y, Miao Y, Zhou H, Jiang G, Wang E
Oncotarget 2017 Sep 19;8(41):70685-70694
Oncotarget 2017 Sep 19;8(41):70685-70694
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Liu L, Mao J, Wang Q, Zhang Z, Wu G, Tang Q, Zhao B, Li L, Li Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:1020-1027
Metformin reverses bFGF-induced epithelial-mesenchymal transition in HCC cells.
Chengye W, Yu T, Ping S, Deguang S, Keyun W, Yan W, Rixin Z, Rui L, Zhenming G, Mingliang Y, Liming W
Oncotarget 2017 Nov 28;8(61):104247-104257
Oncotarget 2017 Nov 28;8(61):104247-104257
HMGA2 regulates epithelial-mesenchymal transition and the acquisition of tumor stem cell properties through TWIST1 in gastric cancer.
Li W, Wang Z, Zha L, Kong D, Liao G, Li H
Oncology reports 2017 Jan;37(1):185-192
Oncology reports 2017 Jan;37(1):185-192
CDH11 inhibits proliferation and invasion in head and neck cancer.
Piao S, Inglehart RC, Scanlon CS, Russo N, Banerjee R, D'Silva NJ
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2017 Feb;46(2):89-97
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2017 Feb;46(2):89-97
AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition.
Zou M, Zhu W, Wang L, Shi L, Gao R, Ou Y, Chen X, Wang Z, Jiang A, Liu K, Xiao M, Ni P, Wu D, He W, Sun G, Li P, Zhai S, Wang X, Hu G
Oncotarget 2016 Mar 15;7(11):13122-38
Oncotarget 2016 Mar 15;7(11):13122-38
Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling.
Liu H, Zhang Q, Li K, Gong Z, Liu Z, Xu Y, Swaney MH, Xiao K, Chen Y
Oncotarget 2016 Dec 6;7(49):81223-81240
Oncotarget 2016 Dec 6;7(49):81223-81240
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TWIST1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TWIST1. This antibody recognizes human antigen. The TWIST1 antibody has been validated for the following applications: ELISA, WB analysis.
