AMM03590G

antibody from Leading Biology

Targeting: GPS2

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03590G

Provider

Leading Biology

Product name

GPS2 Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

3C4

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.