Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- ABIN500214 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Metastasis Associated in Colon Cancer 1 (MACC1) antibody
- Antibody type
- Polyclonal
- Antigen
- MACC1 antibody was raised against a 17 amino acid peptide near the center of humanMACC1.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Submitted references MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis.
Colon cancer metastasis: MACC1 and Met as metastatic pacemakers.
MACC1 controls Met: what a difference an Sp1 site makes.
Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer.
Stein U, Walther W, Arlt F, Schwabe H, Smith J, Fichtner I, Birchmeier W, Schlag PM
Nature medicine 2009 Jan;15(1):59-67
Nature medicine 2009 Jan;15(1):59-67
Colon cancer metastasis: MACC1 and Met as metastatic pacemakers.
Arlt F, Stein U
The international journal of biochemistry & cell biology 2009 Dec;41(12):2356-9
The international journal of biochemistry & cell biology 2009 Dec;41(12):2356-9
MACC1 controls Met: what a difference an Sp1 site makes.
Stein U, Smith J, Walther W, Arlt F
Cell cycle (Georgetown, Tex.) 2009 Aug;8(15):2467-9
Cell cycle (Georgetown, Tex.) 2009 Aug;8(15):2467-9
Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer.
Boardman LA
Genome medicine 2009 Apr 2;1(4):36
Genome medicine 2009 Apr 2;1(4):36
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of MACC1 in mouse liver tissue lysate with AP30528PU-N at (A) 1 and (B) 2 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of MACC1 in human liver tissue with AP30528PU-N at 2.5 ?g/ml.