CABT-L1792

antibody from Creative Diagnostics

Targeting: MALT1 MLT, PCASP1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-L1792

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human MALT1 polyclonal antibody

Antibody type

Polyclonal

Description

MALT-1 was independently identified as a member of the human paracaspase family and an interacting partner of B cell lymphoma. Two alternatively spliced transcript variants encoding different isoforms (a and b) have been described for the MALT-1 gene. Human MALT isoform a is an amino acid protein of 824 amino acids, and human MALT-2 isoform b is an amino acid protein of 813 amino acids. MALT-1 is thought to play a role in NFkappaB signaling by enchancing NF kappaB activation through interaction with BCL-10. Interaction between MALT-1 and BCL-10 mediates IKK activation in vitro through facilitating the ubiquitination of NEMO by the ubiquitin conjugating enzyme UBC13.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.