HPA026975

antibody from Atlas Antibodies

Targeting: ABCB5 ABCB5alpha, ABCB5beta, EST422562

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA026975

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA026975, RRID:AB_10602007

Product name

Anti-ABCB5

Antibody type

Polyclonal

Description

Affinity purified using the PrEST antigen as affinity ligand

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

DLIVTLKDGMLAEKGAHAELMAKRGLYYSLVMSQD
IKKADEQMESMTYSTERKTNSLPLHSVKSIKSDFI
DKAEESTQSKEISLPEVSLL


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Submitted references

The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1.

Mathieu MG, Miles AK, Ahmad M, Buczek ME, Pockley AG, Rees RC, Regad T
Cell death & disease 2014 Feb 13;5(2):e1061

---

ABCB5 expression and cancer stem cell hypothesis in oral squamous cell carcinoma

Grimm M, Krimmel M, Polligkeit J, Alexander D, Munz A, Kluba S, Keutel C, Hoffmann J, Reinert S, Hoefert S
European Journal of Cancer 2012 November;48(17):3186-3197

---

The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo.

Linley AJ, Mathieu MG, Miles AK, Rees RC, McArdle SE, Regad T
The Journal of biological chemistry 2012 Apr 20;287(17):13633-43

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human prostate shows strong granular positivity in glandular cells.