GTX26640

O'Brien MJ, Shu Q, Stinson WA, Tsou PS, Ruth JH, Isozaki T, Campbell PL, Ohara RA, Koch AE, Fox DA, Amin MA
Arthritis research & therapy 2018 Feb 12;20(1):31

Substance P-regulated leukotriene B4 production promotes acute pancreatitis-associated lung injury through neutrophil reverse migration.

Li B, Han X, Ye X, Ni J, Wu J, Dai J, Wu Z, Chen C, Wan R, Wang X, Hu G
International immunopharmacology 2018 Apr;57:147-156

Effect of modulation of PPAR-γ activity on Kupffer cells M1/M2 polarization in the development of non-alcoholic fatty liver disease.

Luo W, Xu Q, Wang Q, Wu H, Hua J
Scientific reports 2017 Mar 16;7:44612

In vivo amelioration of endogenous antitumor autoantibodies via low-dose P4N through the LTA4H/activin A/BAFF pathway.

Lin YL, Tsai NM, Hsieh CH, Ho SY, Chang J, Wu HY, Hsu MH, Chang CC, Liao KW, Jackson TL, Mold DE, Huang RC
Proceedings of the National Academy of Sciences of the United States of America 2016 Nov 29;113(48):E7798-E7807

Vorinostat Modulates the Imbalance of T Cell Subsets, Suppresses Macrophage Activity, and Ameliorates Experimental Autoimmune Uveoretinitis.

Fang S, Meng X, Zhang Z, Wang Y, Liu Y, You C, Yan H
Neuromolecular medicine 2016 Mar;18(1):134-45

Immunodeficient mouse models with different disease profiles by in vivo infection with the same clinical isolate of enterovirus 71.

Liao CC, Liou AT, Chang YS, Wu SY, Chang CS, Lee CK, Kung JT, Tu PH, Yu YY, Lin CY, Lin JS, Shih C
Journal of virology 2014 Nov;88(21):12485-99

CCN1 expression in hepatocytes contributes to macrophage infiltration in nonalcoholic fatty liver disease in mice.

Bian Z, Peng Y, You Z, Wang Q, Miao Q, Liu Y, Han X, Qiu D, Li Z, Ma X
Journal of lipid research 2013 Jan;54(1):44-54

Benzo[a]pyrene potentiates the pathogenesis of abdominal aortic aneurysms in apolipoprotein E knockout mice.

Prins PA, Perati PR, Kon V, Guo Z, Ramesh A, Linton MF, Fazio S, Sampson UK
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;29(1-2):121-30

Zinc oxide nanoparticles-induced intercellular adhesion molecule 1 expression requires Rac1/Cdc42, mixed lineage kinase 3, and c-Jun N-terminal kinase activation in endothelial cells.

Li CH, Liao PL, Shyu MK, Liu CW, Kao CC, Huang SH, Cheng YW, Kang JJ
Toxicological sciences : an official journal of the Society of Toxicology 2012 Mar;126(1):162-72

Abcg2 labels multiple cell types in skeletal muscle and participates in muscle regeneration.

Doyle MJ, Zhou S, Tanaka KK, Pisconti A, Farina NH, Sorrentino BP, Olwin BB
The Journal of cell biology 2011 Oct 3;195(1):147-63

Quantitative estimates of the variability of in vivo sonographic measurements of the mouse aorta for studies of abdominal aortic aneurysms and related arterial diseases.

Sampson UK, Perati PR, Prins PA, Pham W, Liu Z, Harrell FE Jr, Linton MF, Gore JC, Kon V, Fazio S
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2011 Jun;30(6):773-84

Contribution of macrophages to angiogenesis induced by vascular endothelial growth factor receptor-3-specific ligands.

Chung ES, Chauhan SK, Jin Y, Nakao S, Hafezi-Moghadam A, van Rooijen N, Zhang Q, Chen L, Dana R
The American journal of pathology 2009 Nov;175(5):1984-92

The development of abdominal aortic aneurysms in mice is enhanced by benzo(a)pyrene.

Zhang Y, Ramos KS
Vascular health and risk management 2008;4(5):1095-102

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Supportive validation

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Main image
Experimental details: Frozen mouse spleen with Rat anti Mouse F4/80 antigen (GTX26640)

Supportive validation

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Main image
Experimental details: Frozen mouse spleen stained with A: Rat anti Mouse F4/80 (GTX26640) followed by Goat anti Rat IgG:HRP or B: Rat anti Mouse F4/80 (GTX26640) preincubated with 2 molar excess of Human anti Idiotypic followed by Goat anti Rat IgG:HRP

Supportive validation

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Main image
Experimental details: Immunofluorescence image of lymph node stained for macrophages (GTX26640):RPE, red and B cells CD79b, green; nuclei are stained with DAPI, blue

Supportive validation

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Main image
Experimental details: Immunofluorescence image of mouse small intestine stained with Rat anti Mouse F4/80 (GTX26640):RPE, red and Rat anti Mouse CD45, green; nuclei are stained with DAPI, blue. The image higlights macrophages within the lamina propria

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Main image
Experimental details: Staining of J774 cells with Rat anti Mouse F4/80 antigen (GTX26640):Biotin

Supportive validation

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Main image
Experimental details: Staining of J774 cells with Rat anti Mouse F4/80 antigen (GTX26640):Low Endotoxin

Supportive validation

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Main image
Experimental details: Staining of mouse peritoneal macrophage cells with Rat anti Mouse F4/80 antigen (GTX26640):APC

Supportive validation

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Main image
Experimental details: Staining of mouse peritoneal macrophages with Rat anti Mouse F4/80 antigen (GTX26640):FITC

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Staining of mouse peritoneal macrophages with Rat anti Mouse F4/80 antigen (GTX26640)