BS1134

antibody from Bioworld Technology, Inc
Targeting: GABRB1
Provider product page for BS1134
Western blot
Immunohistochemistry

Antibody data

Product number
BS1134 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1134, RRID:AB_1662072
Product name
GABAA RÉÇ1 (R328) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 320-370 of Human GABAA RÉÇ1.
Description
GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA RÏ«1-6, GABAA R ÉÇ1-3, GABAA RÎÛ1-3, GABAA RÑ´, GABAA Rš÷, GABAA RÀÏ1 and GABAA RÀÏ2. The GABAB family is composed of GABAB R1Ï« and GABAB R1ÉÇ. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GABRB1 protein structure - BS1134 shown in red.