BS4078

antibody from Bioworld Technology, Inc
Targeting: GABRB1
Provider product page for BS4078
Western blot
Immunohistochemistry

Antibody data

Product number
BS4078 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GABAA RÉÇ1 (phospho S434) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human GABAA RÉÇ1 around the phosphorylation site of Serine 434.
Description
GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA RÏ«1-6, GABAA R ÉÇ1-3, GABAA RÎÛ1-3, GABAA RÑ´, GABAA Rš÷, GABAA RÀÏ1 and GABAA RÀÏ2. The GABAB family is composed of GABAB R1Ï« and GABAB R1ÉÇ. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GABRB1 protein structure - BS4078 shown in red.