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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2022 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2022, RRID:AB_1570900
- Product name
- ACVR2B polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ACVR2B.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice.
An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors.
Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation.
Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia.
Iwata J, Hacia JG, Suzuki A, Sanchez-Lara PA, Urata M, Chai Y
The Journal of clinical investigation 2012 Mar;122(3):873-85
The Journal of clinical investigation 2012 Mar;122(3):873-85
An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors.
Harrison CA, Gray PC, Fischer WH, Donaldson C, Choe S, Vale W
The Journal of biological chemistry 2004 Jul 2;279(27):28036-44
The Journal of biological chemistry 2004 Jul 2;279(27):28036-44
Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation.
Martins da Silva SJ, Bayne RA, Cambray N, Hartley PS, McNeilly AS, Anderson RA
Developmental biology 2004 Feb 15;266(2):334-45
Developmental biology 2004 Feb 15;266(2):334-45
Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia.
Casagrandi D, Bearfield C, Geary J, Redman CW, Muttukrishna S
Molecular human reproduction 2003 Apr;9(4):199-203
Molecular human reproduction 2003 Apr;9(4):199-203
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of ACVR2B polyclonal antibody (Cat # PAB2022) in mouse heart, kidney and brain lysates (35 ug/lane). ACVR2B (arrow) was detected using the purified Polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with ACVR2B polyclonal antibody (Cat # PAB2022) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
