BAF339

antibody from R&D Systems

Targeting: ACVR2B ActR-IIB

Western blot (Data presented on provider website)

Antibody Data

Product number

BAF339

Provider

R&D Systems

Product name

Human Activin RIIB Biotinylated Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects human Activin RIIB in Western blots. In this format, less than 1% cross-reactivity with recombinant human (rh) Activin RIA, rhActivin RIB, and rhActivin RIIA is observed.

Reactivity

Human

Host

Goat

Conjugate

Biotin

Antigen sequence

CAA54671


Isotype

IgG

Vial size

50 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5.

Bollum LK, Huse K, Oksvold MP, Bai B, Hilden VI, Forfang L, Yoon SO, Wälchli S, Smeland EB, Myklebust JH
PloS one 2017;12(5):e0177188

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Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma.

Huse K, Bakkebø M, Wälchli S, Oksvold MP, Hilden VI, Forfang L, Bredahl ML, Liestøl K, Alizadeh AA, Smeland EB, Myklebust JH
PloS one 2012;7(10):e46117

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Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7.

Huse K, Bakkebø M, Oksvold MP, Forfang L, Hilden VI, Stokke T, Smeland EB, Myklebust JH
European journal of immunology 2011 Nov;41(11):3135-45

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Inhibitory effects and target genes of bone morphogenetic protein 6 in Jurkat TAg cells.

Sivertsen EA, Huse K, Hystad ME, Kersten C, Smeland EB, Myklebust JH
European journal of immunology 2007 Oct;37(10):2937-48

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BMP-6 inhibits human bone marrow B lymphopoiesis--upregulation of Id1 and Id3.

Kersten C, Dosen G, Myklebust JH, Sivertsen EA, Hystad ME, Smeland EB, Rian E
Experimental hematology 2006 Jan;34(1):72-81