Antibody data

Product number
BS5958 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TCP 1š÷ polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 295-340 of Human TCP-1š÷.
Description
The protein TCP-1 (t complex polypeptide 1) is a subunit of the heterooligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species, TCP-1 Ï«, ÉÇ, ÎÛ, Ñ´, š÷, šø, »Ò and IJ, each encoded by a different gene. Two šø subunits have been described: TCP-1 šø (also designated TCP-1 šø1) and TCP-1 šø2. TCP-1 subunits are proposed to have independent functions in folding its in vivo substrates, the actins and tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CCT5 protein structure - BS5958 shown in red.