FNab00674

antibody from FineTest Biotech

Targeting: ATG4B APG4B, AUTL1, DKFZp586D1822, KIAA0943

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ELISA

Immunoprecipitation

Immunohistochemistry

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Validation data

Product number: FNab00674 - Provider product page
Provider: FineTest Biotech
Product name: ATG4B antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: ATG4 autophagy related 4 homolog B
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

ATG4B protein structure - FNab00674 shown in red.