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- References [7]
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- Western blot [2]
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- Flow cytometry [2]
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- Product number
- ABIN151818 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Budding Uninhibited By Benzimidazoles 1 Homolog beta (Yeast) (BUB1B) (AA 1-350), (N-Term) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse
- Host
- Mouse
- Epitope
- N-Term, AA 1-350
- Isotype
- IgG
- Antibody clone number
- 8G1
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Plk1 is upregulated in androgen-insensitive prostate cancer cells and its inhibition leads to necroptosis.
Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis.
A high-content, cell-based screen identifies micropolyin, a new inhibitor of microtubule dynamics.
Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy.
Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability.
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression.
Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC.
Deeraksa A, Pan J, Sha Y, Liu XD, Eissa NT, Lin SH, Yu-Lee LY
Oncogene 2013 Jun 13;32(24):2973-83
Oncogene 2013 Jun 13;32(24):2973-83
Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis.
Silió V, Redondo-Muñoz J, Carrera AC
Molecular biology of the cell 2012 Dec;23(23):4526-42
Molecular biology of the cell 2012 Dec;23(23):4526-42
A high-content, cell-based screen identifies micropolyin, a new inhibitor of microtubule dynamics.
De Rycker M, Rigoreau L, Dowding S, Parker PJ
Chemical biology & drug design 2009 Jun;73(6):599-610
Chemical biology & drug design 2009 Jun;73(6):599-610
Gradual reduction of BUBR1 protein levels results in premature sister-chromatid separation then in aneuploidy.
Bohers E, Sarafan-Vasseur N, Drouet A, Paresy M, Latouche JB, Flaman JM, Sesboüé R, Frebourg T
Human genetics 2008 Dec;124(5):473-8
Human genetics 2008 Dec;124(5):473-8
Dido disruption leads to centrosome amplification and mitotic checkpoint defects compromising chromosome stability.
Trachana V, van Wely KH, Guerrero AA, Fütterer A, Martínez-A C
Proceedings of the National Academy of Sciences of the United States of America 2007 Feb 20;104(8):2691-6
Proceedings of the National Academy of Sciences of the United States of America 2007 Feb 20;104(8):2691-6
Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression.
Johnson VL, Scott MI, Holt SV, Hussein D, Taylor SS
Journal of cell science 2004 Mar 15;117(Pt 8):1577-89
Journal of cell science 2004 Mar 15;117(Pt 8):1577-89
Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC.
Chan GK, Jablonski SA, Sudakin V, Hittle JC, Yen TJ
The Journal of cell biology 1999 Sep 6;146(5):941-54
The Journal of cell biology 1999 Sep 6;146(5):941-54
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