Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 18277-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18277-1-AP, RRID:AB_2255489
- Product name
- STRAP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STRAP antibody (Cat. #18277-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Serine-Threonine Kinase Receptor-Associated Protein (STRAP) Knockout Decreases the Malignant Phenotype in Neuroblastoma Cell Lines.
The noncoding RNA BC200 associates with polysomes to positively regulate mRNA translation in tumor cells.
STRAP as a New Therapeutic Target for Poor Prognosis of Pancreatic Ductal Adenocarcinoma Patients Mainly Caused by TP53 Mutation.
SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability.
Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.
Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
Bownes LV, Williams AP, Marayati R, Quinn CH, Hutchins SC, Stewart JE, Vu T, Easlick JL, Mroczek-Musulman E, Crossman DK, Anderson JC, Willey CD, Datta PK, Beierle EA
Cancers 2021 Jun 26;13(13)
Cancers 2021 Jun 26;13(13)
The noncoding RNA BC200 associates with polysomes to positively regulate mRNA translation in tumor cells.
Booy EP, Gussakovsky D, Choi T, McKenna SA
The Journal of biological chemistry 2021 Jan-Jun;296:100036
The Journal of biological chemistry 2021 Jan-Jun;296:100036
STRAP as a New Therapeutic Target for Poor Prognosis of Pancreatic Ductal Adenocarcinoma Patients Mainly Caused by TP53 Mutation.
Hu S, Chen X, Xu X, Zheng C, Huang W, Zhou Y, Akuetteh PDP, Yang H, Shi K, Chen B, Zhang Q
Frontiers in oncology 2020;10:594224
Frontiers in oncology 2020;10:594224
SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability.
Yu M, Shi X, Ren M, Liu L, Qi H, Zhang C, Zou J, Qiu X, Zhu WG, Zhang YE, Wang W, Luo J
International journal of molecular sciences 2020 Jun 9;21(11)
International journal of molecular sciences 2020 Jun 9;21(11)
Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.
Booy EP, McRae EK, Ezzati P, Choi T, Gussakovsky D, McKenna SA
Nucleic acids research 2018 Nov 30;46(21):11575-11591
Nucleic acids research 2018 Nov 30;46(21):11575-11591
Downregulation of STRAP promotes tumor growth and metastasis in hepatocellular carcinoma via reducing PTEN level.
Wu Q, Yu S, Chen J, Li Y, Gao Y
IUBMB life 2018 Feb;70(2):120-128
IUBMB life 2018 Feb;70(2):120-128
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
Khan MR, Xiang S, Song Z, Wu M
The EMBO journal 2017 Dec 1;36(23):3483-3500
The EMBO journal 2017 Dec 1;36(23):3483-3500
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 18277-1-AP(STRAP antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-STRAP (IP:18277-1-AP, 4ug; Detection:18277-1-AP 1:2000) with HeLa cells lysate 2000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary using 18277-1-AP(STRAP antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STRAP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human STRAP. This antibody recognizes human,mouse,rat antigen. The STRAP antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.