Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10569-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10569-1-AP, RRID:AB_2130060
- Product name
- Integrin Alpha-5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Integrin Alpha-5 antibody (Cat. #10569-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, monkey and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ursolic Acid Regulates Intestinal Microbiota and Inflammatory Cell Infiltration to Prevent Ulcerative Colitis.
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
Role of vasodilator-stimulated phosphoprotein in RANKL-differentiated murine macrophage RAW264.7 cells: Modulation of NF-κB, c-Fos and NFATc1 transcription factors.
The cell surface hyaluronidase TMEM2 regulates cell adhesion and migration via degradation of hyaluronan at focal adhesion sites.
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Identification of rare variants in cardiac sodium channel β4-subunit gene SCN4B associated with ventricular tachycardia.
Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins.
Quantitative Proteomics Implicates Rictor/mTORC2 in Cell Adhesion.
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy.
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment.
Integrin endocytosis on elastic substrates mediates mechanosensing.
CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells.
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Sheng Q, Li F, Chen G, Li J, Li J, Wang Y, Lu Y, Li Q, Li M, Chai K
Journal of immunology research 2021;2021:6679316
Journal of immunology research 2021;2021:6679316
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.
Kazan JM, Desrochers G, Martin CE, Jeong H, Kharitidi D, Apaja PM, Roldan A, St Denis N, Gingras AC, Lukacs GL, Pause A
iScience 2021 Nov 19;24(11):103274
iScience 2021 Nov 19;24(11):103274
Role of vasodilator-stimulated phosphoprotein in RANKL-differentiated murine macrophage RAW264.7 cells: Modulation of NF-κB, c-Fos and NFATc1 transcription factors.
Hu H, Li C, Zhang H, Wu G, Huang Y
Experimental and therapeutic medicine 2021 May;21(5):412
Experimental and therapeutic medicine 2021 May;21(5):412
The cell surface hyaluronidase TMEM2 regulates cell adhesion and migration via degradation of hyaluronan at focal adhesion sites.
Irie F, Tobisawa Y, Murao A, Yamamoto H, Ohyama C, Yamaguchi Y
The Journal of biological chemistry 2021 Jan-Jun;296:100481
The Journal of biological chemistry 2021 Jan-Jun;296:100481
Angiopoietin 2 stimulates trophoblast invasion via a mechanism associated with JNK signaling.
Hou H, Ning F, Zhang JY, Lu Q, Zhang M, Wu P, Chen M, Lash GE
Molecular human reproduction 2021 Feb 27;27(3)
Molecular human reproduction 2021 Feb 27;27(3)
Identification of rare variants in cardiac sodium channel β4-subunit gene SCN4B associated with ventricular tachycardia.
Yang Q, Xiong H, Xu C, Huang Y, Tu X, Wu G, Fu F, Wang Z, Wang L, Zhao Y, Li S, Huang Y, Wang C, Wang D, Yao Y, Wang F, Wang Y, Xue Y, Wang P, Chen Q, Pu J, Wang QK
Molecular genetics and genomics : MGG 2019 Aug;294(4):1059-1071
Molecular genetics and genomics : MGG 2019 Aug;294(4):1059-1071
Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins.
Zhong B, Wang K, Xu H, Kong F
Cancer cell international 2018;18:79
Cancer cell international 2018;18:79
Quantitative Proteomics Implicates Rictor/mTORC2 in Cell Adhesion.
Wang H, Shao X, He Q, Wang C, Xia L, Yue D, Qin G, Jia C, Chen R
Journal of proteome research 2018 Oct 5;17(10):3360-3369
Journal of proteome research 2018 Oct 5;17(10):3360-3369
Osteogenesis potential of different titania nanotubes in oxidative stress microenvironment.
Yu Y, Shen X, Luo Z, Hu Y, Li M, Ma P, Ran Q, Dai L, He Y, Cai K
Biomaterials 2018 Jun;167:44-57
Biomaterials 2018 Jun;167:44-57
Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy.
Qiu Y, Yu Q, Liu Y, Tang J, Wang X, Lu Z, Xu Z, He Q
Pharmaceutical research 2018 Apr 26;35(7):130
Pharmaceutical research 2018 Apr 26;35(7):130
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Xu L, Yin L, Tao X, Qi Y, Han X, Xu Y, Song S, Li L, Sun P, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Annexin A4 fucosylation enhances its interaction with the NF-kB p50 and promotes tumor progression of ovarian clear cell carcinoma.
Wang H, Deng L, Cai M, Zhuang H, Zhu L, Hao Y, Gao J, Liu J, Li X, Lin B
Oncotarget 2017 Dec 8;8(64):108093-108107
Oncotarget 2017 Dec 8;8(64):108093-108107
Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment.
Zarone MR, Misso G, Grimaldi A, Zappavigna S, Russo M, Amler E, Di Martino MT, Amodio N, Tagliaferri P, Tassone P, Caraglia M
Scientific reports 2017 Dec 20;7(1):17949
Scientific reports 2017 Dec 20;7(1):17949
Integrin endocytosis on elastic substrates mediates mechanosensing.
Li J, Chen H, Xu Y, Hu J, Xie FQ, Yang C
Journal of biomechanics 2016 Sep 6;49(13):2644-2654
Journal of biomechanics 2016 Sep 6;49(13):2644-2654
CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells.
Haraguchi M, Sato M, Ozawa M
PloS one 2015;10(7):e0132260
PloS one 2015;10(7):e0132260
Sine oculis homeobox homolog 1 promotes α5β1-mediated invasive migration and metastasis of cervical cancer cells.
Liu D, Zhang XX, Wan DY, Xi BX, Ma D, Wang H, Gao QL
Biochemical and biophysical research communications 2014 Apr 4;446(2):549-54
Biochemical and biophysical research communications 2014 Apr 4;446(2):549-54
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The Integrin alpha-5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Integrin alpha-5. This antibody recognizes human, mouse, monkey antigen. The Integrin alpha-5 antibody has been validated for the following applications: ELISA, WB analysis.