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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Immunocytochemistry [2]
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- Product number
- ADI-AAP-113-D - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ADI-AAP-113-D, RRID:AB_2038936
- Product name
- Caspase-3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length protein
- Description
- Protein A affinity purified.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Chicken/Avian, Guinea Pig, Hamster, Porcine, Rabbit, Simian, Yeast
- Host
- Rabbit
- Vial size
- 50 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma.
Characterization of stress response in human retinal epithelial cells.
Carfilzomib and ONX 0912 inhibit cell survival and tumor growth of head and neck cancer and their activities are enhanced by suppression of Mcl-1 or autophagy.
Sodium butyrate with UCN-01 has marked antitumour activity against cervical cancer cells.
Elevated retina-specific expression of the small heat shock protein, alphaA-crystallin, is associated with photoreceptor protection in experimental uveitis.
Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death.
Activation of caspase pathways during iron chelator-mediated apoptosis.
Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells.
Hu W, Jin L, Jiang CC, Long GV, Scolyer RA, Wu Q, Zhang XD, Mei Y, Wu M
Cell death & disease 2013 Nov 7;4:e914
Cell death & disease 2013 Nov 7;4:e914
Characterization of stress response in human retinal epithelial cells.
Giansanti V, Rodriguez GE, Savoldelli M, Gioia R, Forlino A, Mazzini G, Pennati M, Zaffaroni N, Scovassi AI, Torriglia A
Journal of cellular and molecular medicine 2013 Jan;17(1):103-15
Journal of cellular and molecular medicine 2013 Jan;17(1):103-15
Carfilzomib and ONX 0912 inhibit cell survival and tumor growth of head and neck cancer and their activities are enhanced by suppression of Mcl-1 or autophagy.
Zang Y, Thomas SM, Chan ET, Kirk CJ, Freilino ML, DeLancey HM, Grandis JR, Li C, Johnson DE
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Oct 15;18(20):5639-49
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Oct 15;18(20):5639-49
Sodium butyrate with UCN-01 has marked antitumour activity against cervical cancer cells.
Decrion-Barthod AZ, Bosset M, Plissonnier ML, Marchini A, Nicolier M, Launay S, Prétet JL, Rommelaere J, Mougin C
Anticancer research 2010 Oct;30(10):4049-61
Anticancer research 2010 Oct;30(10):4049-61
Elevated retina-specific expression of the small heat shock protein, alphaA-crystallin, is associated with photoreceptor protection in experimental uveitis.
Rao NA, Saraswathy S, Wu GS, Katselis GS, Wawrousek EF, Bhat S
Investigative ophthalmology & visual science 2008 Mar;49(3):1161-71
Investigative ophthalmology & visual science 2008 Mar;49(3):1161-71
Inhibition of p53 protects liver tissue against endotoxin-induced apoptotic and necrotic cell death.
Schäfer T, Scheuer C, Roemer K, Menger MD, Vollmar B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 Apr;17(6):660-7
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 Apr;17(6):660-7
Activation of caspase pathways during iron chelator-mediated apoptosis.
Greene BT, Thorburn J, Willingham MC, Thorburn A, Planalp RP, Brechbiel MW, Jennings-Gee J, Wilkinson J 4th, Torti FM, Torti SV
The Journal of biological chemistry 2002 Jul 12;277(28):25568-75
The Journal of biological chemistry 2002 Jul 12;277(28):25568-75
Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells.
Xiao C, Yang BF, Asadi N, Beguinot F, Hao C
The Journal of biological chemistry 2002 Jul 12;277(28):25020-5
The Journal of biological chemistry 2002 Jul 12;277(28):25020-5
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of Caspase-3 pAb: Lane 1: MW Marker, Lane 2: Jurkat (Prod. No. ADI-LYC-JK100), Lane 3: Jurkat treated with staurosporine, Lane 4: MCF-7 (negative control), Lane 5: HeLa, (cell lysate) (Prod. No. ADI-LYC-HL100), Lane 6: Rat Spleen, Lane 7: Mouse Spleen.
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of human spleen tissue stained with Caspase-3, pAb at 10µg/ml.
