CABT-B12272
antibody from Creative Diagnostics
Targeting: CLEC4M
CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN
Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B12272 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Human anti-Human CLEC4M recombinant monoclonal antibody, clone SFB698 [PE]
- Antibody type
- Monoclonal
- Description
- It recognozes the human CD299 (L-SIGN) antigen, a type II integral membrane protein, also known as C-type lectin domain family 4 member M (CLEC4M) or liver/lymph node-specific ICAM-3-grabbing non-integrin. CD299 is expressed by sinusoidal endothelial cells in lymph nodes and is found in placental endothelium but not in macrophages. It is also expressed in type II alveolar cells and lung endothelial cells. CD299 has a high affinity for both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. Additional information: It displays negligible binding to Fc receptors.
- Reactivity
- Human
- Host
- Human
- Conjugate
- Yellow dye
- Isotype
- IgG
- Antibody clone number
- SFB698
- Vial size
- for 100 tests
- Storage
- Store protected from light at 2ÿ8 °C. Do not freeze.
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