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LearnMAB162
antibody from R&D Systems
Targeting: CLEC4M
CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- MAB162 - Provider product page
- Provider
- R&D Systems
- Product name
- Human DC-SIGNR/CD299 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human DC-SIGNR/CD299.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Q9H2X3- Isotype
- IgG
- Antibody clone number
- 120604
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity.
Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2.
Adhesion of human haematopoietic (CD34+) stem cells to human liver compartments is integrin and CD44 dependent and modulated by CXCR3 and CXCR4.
DC-SIGN mediates cell-free infection and transmission of human T-cell lymphotropic virus type 1 by dendritic cells.
Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction.
L-SIGN (CD209L) isoforms differently mediate trans-infection of hepatoma cells by hepatitis C virus pseudoparticles.
DC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by platelets.
Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles.
Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosomal degradation.
Swystun LL, Lai JD, Notley C, Georgescu I, Paine AS, Mewburn J, Nesbitt K, Schledzewski K, Géraud C, Kzhyshkowska J, Goerdt S, Hopman W, Montgomery RR, James PD, Lillicrap D
The Journal of clinical investigation 2018 Aug 31;128(9):4057-4073
The Journal of clinical investigation 2018 Aug 31;128(9):4057-4073
Respiratory syncytial virus glycoprotein G interacts with DC-SIGN and L-SIGN to activate ERK1 and ERK2.
Johnson TR, McLellan JS, Graham BS
Journal of virology 2012 Feb;86(3):1339-47
Journal of virology 2012 Feb;86(3):1339-47
Adhesion of human haematopoietic (CD34+) stem cells to human liver compartments is integrin and CD44 dependent and modulated by CXCR3 and CXCR4.
Crosby HA, Lalor PF, Ross E, Newsome PN, Adams DH
Journal of hepatology 2009 Oct;51(4):734-49
Journal of hepatology 2009 Oct;51(4):734-49
DC-SIGN mediates cell-free infection and transmission of human T-cell lymphotropic virus type 1 by dendritic cells.
Jain P, Manuel SL, Khan ZK, Ahuja J, Quann K, Wigdahl B
Journal of virology 2009 Nov;83(21):10908-21
Journal of virology 2009 Nov;83(21):10908-21
Human liver sinusoidal endothelial cells induce apoptosis in activated T cells: a role in tolerance induction.
Karrar A, Broomé U, Uzunel M, Qureshi AR, Sumitran-Holgersson S
Gut 2007 Feb;56(2):243-52
Gut 2007 Feb;56(2):243-52
L-SIGN (CD209L) isoforms differently mediate trans-infection of hepatoma cells by hepatitis C virus pseudoparticles.
Falkowska E, Durso RJ, Gardner JP, Cormier EG, Arrigale RA, Ogawa RN, Donovan GP, Maddon PJ, Olson WC, Dragic T
The Journal of general virology 2006 Sep;87(Pt 9):2571-6
The Journal of general virology 2006 Sep;87(Pt 9):2571-6
DC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by platelets.
Chaipan C, Soilleux EJ, Simpson P, Hofmann H, Gramberg T, Marzi A, Geier M, Stewart EA, Eisemann J, Steinkasserer A, Suzuki-Inoue K, Fuller GL, Pearce AC, Watson SP, Hoxie JA, Baribaud F, Pöhlmann S
Journal of virology 2006 Sep;80(18):8951-60
Journal of virology 2006 Sep;80(18):8951-60
Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles.
Lai WK, Sun PJ, Zhang J, Jennings A, Lalor PF, Hubscher S, McKeating JA, Adams DH
The American journal of pathology 2006 Jul;169(1):200-8
The American journal of pathology 2006 Jul;169(1):200-8
Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosomal degradation.
Ludwig IS, Lekkerkerker AN, Depla E, Bosman F, Musters RJ, Depraetere S, van Kooyk Y, Geijtenbeek TB
Journal of virology 2004 Aug;78(15):8322-32
Journal of virology 2004 Aug;78(15):8322-32
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of DC-SIGNR/CD299 in Human DC-SIGNR/CD299 Transfected 3T3 Mouse Cell Line by Flow Cytometry. Human DC-SIGNR/CD299 and DC-SIGN transfected 3T3 mouse embryonic fibroblast cell line were stained with Mouse Anti-Human DC-SIGNR/CD299 Monoclonal Antibody (Catalog # MAB162, filled histograms) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0102B).
