BS6018

antibody from Bioworld Technology, Inc
Targeting: KRT19 CK19, K19, K1CS, MGC15366
Provider product page for BS6018
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6018 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Cytokeratin 19 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human Cytokeratin 19.
Description
Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells and have been found to be useful markers of tissue differentiation, which is directly applicable to the characterization of malignant tumors. For example, many types of cancer cells express Cytokeratin 19 (CK19), an epithelial cytoskeletal protein within the suprabasal squamous epithelium. Cytokeratin 19 is a specific marker of moderate to severe dysplasia and carcinoma in situ in oral cavity squamous epithelium, and measurement of Cytokeratin 19 may be a useful marker in diagnosing hepatoma. Cytokeratin 19 fragment levels in serum have been documented as a marker for lung cancer. Clinical investigations have suggested that serum CYFRA 21-1, a fragment of Cytokeratin 19, may be among the most useful tumor markers.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
KRT19 protein structure - BS6018 shown in red.