Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN258315 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1) (AA 1-100), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Guinea Pig
- Host
- Rabbit
- Epitope
- N-Term, AA 1-100
- Vial size
- 0.1 mL
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references TRPA1 expression is downregulated by dexamethasone and aurothiomalate in human chondrocytes: TRPA1 as a novel factor and drug target in arthritis.
Mast cell hyperactivity underpins the development of oxygen-induced retinopathy.
Loss of Transient Receptor Potential Ankyrin 1 Channel Deregulates Emotion, Learning and Memory, Cognition, and Social Behavior in Mice.
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.
Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation.
Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice.
Transient Receptor Potential Ankyrin 1 Activation within the Cardiac Myocyte Limits Ischemia-reperfusion Injury in Rodents.
Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease.
TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response.
Roles of Cav3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis.
Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
A Potent and Site-Selective Agonist of TRPA1.
Transient receptor potential vanilloid 4 (TRPV4) is downregulated in keratinocytes in human non-melanoma skin cancer.
TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis.
Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice.
Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells.
Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine.
Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice.
TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus.
Nummenmaa E, Hämäläinen M, Moilanen LJ, Moilanen T, Vuolteenaho K, Moilanen E
RMD open 2017;3(2):e000556
RMD open 2017;3(2):e000556
Mast cell hyperactivity underpins the development of oxygen-induced retinopathy.
Matsuda K, Okamoto N, Kondo M, Arkwright PD, Karasawa K, Ishizaka S, Yokota S, Matsuda A, Jung K, Oida K, Amagai Y, Jang H, Noda E, Kakinuma R, Yasui K, Kaku U, Mori Y, Onai N, Ohteki T, Tanaka A, Matsuda H
The Journal of clinical investigation 2017 Nov 1;127(11):3987-4000
The Journal of clinical investigation 2017 Nov 1;127(11):3987-4000
Loss of Transient Receptor Potential Ankyrin 1 Channel Deregulates Emotion, Learning and Memory, Cognition, and Social Behavior in Mice.
Lee KI, Lin HC, Lee HT, Tsai FC, Lee TS
Molecular neurobiology 2017 Jul;54(5):3606-3617
Molecular neurobiology 2017 Jul;54(5):3606-3617
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.
Hidaka T, Ogawa E, Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Fujimura T, Aiba S, Nakayama K, Okuyama R, Yamamoto M
Nature immunology 2017 Jan;18(1):64-73
Nature immunology 2017 Jan;18(1):64-73
Notch1-promoted TRPA1 expression in erythroleukemic cells suppresses erythroid but enhances megakaryocyte differentiation.
Chen JL, Ping YH, Tseng MJ, Chang YI, Lee HC, Hsieh RH, Yeh TS
Scientific reports 2017 Feb 21;7:42883
Scientific reports 2017 Feb 21;7:42883
Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice.
De Logu F, Nassini R, Materazzi S, Carvalho Gonçalves M, Nosi D, Rossi Degl'Innocenti D, Marone IM, Ferreira J, Li Puma S, Benemei S, Trevisan G, Souza Monteiro de Araújo D, Patacchini R, Bunnett NW, Geppetti P
Nature communications 2017 Dec 1;8(1):1887
Nature communications 2017 Dec 1;8(1):1887
Transient Receptor Potential Ankyrin 1 Activation within the Cardiac Myocyte Limits Ischemia-reperfusion Injury in Rodents.
Lu Y, Piplani H, McAllister SL, Hurt CM, Gross ER
Anesthesiology 2016 Dec;125(6):1171-1180
Anesthesiology 2016 Dec;125(6):1171-1180
Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease.
Lee KI, Lee HT, Lin HC, Tsay HJ, Tsai FC, Shyue SK, Lee TS
Journal of neuroinflammation 2016 Apr 27;13(1):92
Journal of neuroinflammation 2016 Apr 27;13(1):92
TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response.
Billeter AT, Galbraith N, Walker S, Lawson C, Gardner SA, Sarojini H, Galandiuk S, Polk HC Jr
Surgery 2015 Sep;158(3):646-54
Surgery 2015 Sep;158(3):646-54
Roles of Cav3.2 and TRPA1 channels targeted by hydrogen sulfide in pancreatic nociceptive processing in mice with or without acute pancreatitis.
Terada Y, Fujimura M, Nishimura S, Tsubota M, Sekiguchi F, Kawabata A
Journal of neuroscience research 2015 Feb;93(2):361-9
Journal of neuroscience research 2015 Feb;93(2):361-9
Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain.
Weng HJ, Patel KN, Jeske NA, Bierbower SM, Zou W, Tiwari V, Zheng Q, Tang Z, Mo GC, Wang Y, Geng Y, Zhang J, Guan Y, Akopian AN, Dong X
Neuron 2015 Feb 18;85(4):833-46
Neuron 2015 Feb 18;85(4):833-46
A Potent and Site-Selective Agonist of TRPA1.
Takaya J, Mio K, Shiraishi T, Kurokawa T, Otsuka S, Mori Y, Uesugi M
Journal of the American Chemical Society 2015 Dec 23;137(50):15859-64
Journal of the American Chemical Society 2015 Dec 23;137(50):15859-64
Transient receptor potential vanilloid 4 (TRPV4) is downregulated in keratinocytes in human non-melanoma skin cancer.
Fusi C, Materazzi S, Minocci D, Maio V, Oranges T, Massi D, Nassini R
The Journal of investigative dermatology 2014 Sep;134(9):2408-2417
The Journal of investigative dermatology 2014 Sep;134(9):2408-2417
TRPA1-dependent pruritus in IL-13-induced chronic atopic dermatitis.
Oh MH, Oh SY, Lu J, Lou H, Myers AC, Zhu Z, Zheng T
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5371-82
Journal of immunology (Baltimore, Md. : 1950) 2013 Dec 1;191(11):5371-82
Hydrogen sulfide-induced mechanical hyperalgesia and allodynia require activation of both Cav3.2 and TRPA1 channels in mice.
Okubo K, Matsumura M, Kawaishi Y, Aoki Y, Matsunami M, Okawa Y, Sekiguchi F, Kawabata A
British journal of pharmacology 2012 Jul;166(5):1738-43
British journal of pharmacology 2012 Jul;166(5):1738-43
Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells.
Mukhopadhyay I, Gomes P, Aranake S, Shetty M, Karnik P, Damle M, Kuruganti S, Thorat S, Khairatkar-Joshi N
Journal of receptor and signal transduction research 2011 Oct;31(5):350-8
Journal of receptor and signal transduction research 2011 Oct;31(5):350-8
Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine.
Poole DP, Pelayo JC, Cattaruzza F, Kuo YM, Gai G, Chiu JV, Bron R, Furness JB, Grady EF, Bunnett NW
Gastroenterology 2011 Aug;141(2):565-75, 575.e1-4
Gastroenterology 2011 Aug;141(2):565-75, 575.e1-4
Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice.
Cattaruzza F, Spreadbury I, Miranda-Morales M, Grady EF, Vanner S, Bunnett NW
American journal of physiology. Gastrointestinal and liver physiology 2010 Jan;298(1):G81-91
American journal of physiology. Gastrointestinal and liver physiology 2010 Jan;298(1):G81-91
TRPA1 in mast cell activation-induced long-lasting mechanical hypersensitivity of vagal afferent C-fibers in guinea pig esophagus.
Yu S, Gao G, Peterson BZ, Ouyang A
American journal of physiology. Gastrointestinal and liver physiology 2009 Jul;297(1):G34-42
American journal of physiology. Gastrointestinal and liver physiology 2009 Jul;297(1):G34-42
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