GTX15442

antibody from GeneTex

Targeting: SLCO1B3 OATP1B3, OATP8, SLC21A8

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

GTX15442

Provider

GeneTex

Proper citation

GeneTex Cat#GTX15442, RRID:AB_372564

Product name

OATP8 antibody [MDQ]

Antibody type

Monoclonal

Reactivity

Human, Mouse

Host

Mouse

Storage

-20¢X C, Avoid Freeze/Thaw Cycles

References

Submitted references

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

van de Steeg E, Stránecký V, Hartmannová H, Nosková L, Hřebíček M, Wagenaar E, van Esch A, de Waart DR, Oude Elferink RP, Kenworthy KE, Sticová E, al-Edreesi M, Knisely AS, Kmoch S, Jirsa M, Schinkel AH
The Journal of clinical investigation 2012 Feb;122(2):519-28

Immunocytochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunofluorescent analysis of OATP8 in HepG2 cells. Cells were grown on slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with OATP8 antibody [MDQ] at a dilution of 1:20 overnight at 4 C, washed with PBS and incubated with a proper secondary antibody. OATP8 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.