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- References [13]
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- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 10105-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10105-2-AP, RRID:AB_2211478
- Product name
- UBE2T/HSPC150 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated UBE2T/HSPC150 antibody (Cat. #10105-2-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Comprehensive analysis of differentially expressed genes reveals the promotive effects of UBE2T on colorectal cancer cell proliferation.
Increased Expression of UBE2T Predicting Poor Survival of Epithelial Ovarian Cancer: Based on Comprehensive Analysis of UBE2s, Clinical Samples, and the GEO Database.
Affinity-based protein profiling to reveal targets of puerarin involved in its protective effect on cardiomyocytes.
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Expression of ubiquitin-conjugating enzyme E2T in colorectal cancers and clinical implications.
UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma.
A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity.
Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma.
Ubiquitin-Conjugating Enzyme E2T is an Independent Prognostic Factor and Promotes Gastric Cancer Progression.
UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway.
Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.
Elevated expression of UBE2T in lung cancer tumors and cell lines.
Proteasome function is required for DNA damage response and fanconi anemia pathway activation.
Luo M, Zhou Y
Oncology letters 2021 Oct;22(4):714
Oncology letters 2021 Oct;22(4):714
Increased Expression of UBE2T Predicting Poor Survival of Epithelial Ovarian Cancer: Based on Comprehensive Analysis of UBE2s, Clinical Samples, and the GEO Database.
Zou R, Xu H, Li F, Wang S, Zhu L
DNA and cell biology 2021 Jan;40(1):36-60
DNA and cell biology 2021 Jan;40(1):36-60
Affinity-based protein profiling to reveal targets of puerarin involved in its protective effect on cardiomyocytes.
Huang S, Wang FJ, Lin H, Liu T, Zhao CX, Chen LG
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111160
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Feb;134:111160
UBE2T-regulated H2AX monoubiquitination induces hepatocellular carcinoma radioresistance by facilitating CHK1 activation.
Sun J, Zhu Z, Li W, Shen M, Cao C, Sun Q, Guo Z, Liu L, Wu D
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
Journal of experimental & clinical cancer research : CR 2020 Oct 21;39(1):222
Expression of ubiquitin-conjugating enzyme E2T in colorectal cancers and clinical implications.
Wu X, Liu G, Liu R, He J, Wang G, Zhang H, Liu T, Bai J, Cheng N, Qiu J
Oncology letters 2020 Nov;20(5):275
Oncology letters 2020 Nov;20(5):275
UBE2T promotes proliferation via G2/M checkpoint in hepatocellular carcinoma.
Liu LL, Zhu JM, Yu XN, Zhu HR, Shi X, Bilegsaikhan E, Guo HY, Wu J, Shen XZ
Cancer management and research 2019;11:8359-8370
Cancer management and research 2019;11:8359-8370
A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity.
Vila IK, Park MK, Setijono SR, Yao Y, Kim H, Badin PM, Choi S, Narkar V, Choi SW, Chung J, Moro C, Song SJ, Song MS
JCI insight 2019 Jul 11;4(13)
JCI insight 2019 Jul 11;4(13)
Amplification and overexpression of E2 ubiquitin conjugase UBE2T promotes homologous recombination in multiple myeloma.
Alagpulinsa DA, Kumar S, Talluri S, Nanjappa P, Buon L, Chakraborty C, Samur MK, Szalat R, Shammas MA, Munshi NC
Blood advances 2019 Dec 10;3(23):3968-3972
Blood advances 2019 Dec 10;3(23):3968-3972
Ubiquitin-Conjugating Enzyme E2T is an Independent Prognostic Factor and Promotes Gastric Cancer Progression.
Yu H, Xiang P, Pan Q, Huang Y, Xie N, Zhu W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):11723-11732
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Sep;37(9):11723-11732
UBE2T promotes nasopharyngeal carcinoma cell proliferation, invasion, and metastasis by activating the AKT/GSK3β/β-catenin pathway.
Hu W, Xiao L, Cao C, Hua S, Wu D
Oncotarget 2016 Mar 22;7(12):15161-72
Oncotarget 2016 Mar 22;7(12):15161-72
Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia.
Hira A, Yoshida K, Sato K, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Shimamoto A, Tahara H, Ito E, Kojima S, Kurumizaka H, Ogawa S, Takata M, Yabe H, Yabe M
American journal of human genetics 2015 Jun 4;96(6):1001-7
American journal of human genetics 2015 Jun 4;96(6):1001-7
Elevated expression of UBE2T in lung cancer tumors and cell lines.
Hao J, Xu A, Xie X, Hao J, Tian T, Gao S, Xiao X, He D
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2008;29(3):195-203
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2008;29(3):195-203
Proteasome function is required for DNA damage response and fanconi anemia pathway activation.
Jacquemont C, Taniguchi T
Cancer research 2007 Aug 1;67(15):7395-405
Cancer research 2007 Aug 1;67(15):7395-405
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10105-2-AP(UBE2T antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using UBE2T antibody 10105-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
