HOXA3

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

Homeobox A3

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

7 (27106184 - 27152581)

Ensembl ID

ENSG00000105997  (ver. 103.38)

Orthologs

Mouse Hoxa3: ENSMUSG00000079560

UniProt

O43365

neXtProt

NX_O43365

Human splice variants
Mouse splice variants

Protein structure