11-12020

antibody from ABEOMICS Inc.
Targeting: HOXA9 HOX1, HOX1G
Provider product page for 11-12020

Antibody data

Product number
11-12020 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-HOXA9 Antibody
Antibody type
Polyclonal
Description
HOXA9 is a well-studied member of the HOXA cluster, and it plays a significant role in both normal hematopoiesis and leukemogenesis. HOXA9 is expressed in EC (Endothelial Cells) and its expression is rapidly downregulated during EC activation by inflammatory signals like TNF-alpha (Tumor Necrosis Factor-Alpha) and LPS (lipopolysaccharide) . In humans,HOXA9 was found to be highly expressed and required in some subtypes of leukemia, particularly mixed lineage leukemia (MLL)-rearranged leukemia. The aberrant overexpression of HOXA9 is thought to be associated with poor survival of acute myeloid leukemia (AML) patients.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant HOXA9
protein (amino acids 63-272) was us
ed as the immunogen for this antibo
dy.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
HOXA9 protein structure - 11-12020 shown in red.