Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 16277-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16277-1-AP, RRID:AB_2181292
- Product name
- RPL11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RPL11 antibody (Cat. #16277-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein Synthesis.
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Control of ribosomal protein synthesis by the Microprocessor complex.
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
RPL32 Promotes Lung Cancer Progression by Facilitating p53 Degradation.
Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level.
Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome.
Cellular sensitivity to UV-irradiation is mediated by RNA polymerase I transcription.
FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination.
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis.
Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway.
The ribosomal protein S26 regulates p53 activity in response to DNA damage.
Regulation of Actinomycin D induced upregulation of Mdm2 in H1299 cells.
Defective ribosome assembly in Shwachman-Diamond syndrome.
Jia F, Wu Q, Wang Z, Zhang M, Yuan S, Che Y, Li B, Hu Z, Hu X
Oxidative medicine and cellular longevity 2021;2021:5986260
Oxidative medicine and cellular longevity 2021;2021:5986260
Cilia locally synthesize proteins to sustain their ultrastructure and functions.
Hao K, Chen Y, Yan X, Zhu X
Nature communications 2021 Nov 30;12(1):6971
Nature communications 2021 Nov 30;12(1):6971
Control of ribosomal protein synthesis by the Microprocessor complex.
Jiang X, Prabhakar A, Van der Voorn SM, Ghatpande P, Celona B, Venkataramanan S, Calviello L, Lin C, Wang W, Black BL, Floor SN, Lagna G, Hata A
Science signaling 2021 Feb 23;14(671)
Science signaling 2021 Feb 23;14(671)
Genomic gain of RRS1 promotes hepatocellular carcinoma through reducing the RPL11-MDM2-p53 signaling.
Cao P, Yang A, Li P, Xia X, Han Y, Zhou G, Wang R, Yang F, Li Y, Zhang Y, Cui Y, Ji H, Lu L, He F, Zhou G
Science advances 2021 Aug;7(35)
Science advances 2021 Aug;7(35)
Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.
Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
Developmental cell 2021 Aug 23;56(16):2313-2328.e7
RPL32 Promotes Lung Cancer Progression by Facilitating p53 Degradation.
Xie J, Zhang W, Liang X, Shuai C, Zhou Y, Pan H, Yang Y, Han W
Molecular therapy. Nucleic acids 2020 Sep 4;21:75-85
Molecular therapy. Nucleic acids 2020 Sep 4;21:75-85
Knockdown of the Ribosomal Protein eL29 in Mammalian Cells Leads to Significant Changes in Gene Expression at the Transcription Level.
Gopanenko AV, Kolobova AV, Meschaninova MI, Venyaminova AG, Tupikin AE, Kabilov MR, Malygin AA, Karpova GG
Cells 2020 May 15;9(5)
Cells 2020 May 15;9(5)
Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome.
Alupei MC, Maity P, Esser PR, Krikki I, Tuorto F, Parlato R, Penzo M, Schelling A, Laugel V, Montanaro L, Scharffetter-Kochanek K, Iben S
Cell reports 2018 May 8;23(6):1612-1619
Cell reports 2018 May 8;23(6):1612-1619
Cellular sensitivity to UV-irradiation is mediated by RNA polymerase I transcription.
Assfalg R, Alupei MC, Wagner M, Koch S, Gonzalez OG, Schelling A, Scharffetter-Kochanek K, Iben S
PloS one 2017;12(6):e0179843
PloS one 2017;12(6):e0179843
FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination.
Neben CL, Tuzon CT, Mao X, Lay FD, Merrill AE
Human molecular genetics 2017 Sep 1;26(17):3253-3270
Human molecular genetics 2017 Sep 1;26(17):3253-3270
RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice.
Jiang L, Li T, Zhang X, Zhang B, Yu C, Li Y, Fan S, Jiang X, Khan T, Hao Q, Xu P, Nadano D, Huleihel M, Lunenfeld E, Wang PJ, Zhang Y, Shi Q
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Current biology : CB 2017 May 22;27(10):1498-1505.e6
Partial Loss of Rpl11 in Adult Mice Recapitulates Diamond-Blackfan Anemia and Promotes Lymphomagenesis.
Morgado-Palacin L, Varetti G, Llanos S, Gómez-López G, Martinez D, Serrano M
Cell reports 2015 Oct 27;13(4):712-722
Cell reports 2015 Oct 27;13(4):712-722
Non-genotoxic activation of p53 through the RPL11-dependent ribosomal stress pathway.
Morgado-Palacin L, Llanos S, Urbano-Cuadrado M, Blanco-Aparicio C, Megias D, Pastor J, Serrano M
Carcinogenesis 2014 Dec;35(12):2822-30
Carcinogenesis 2014 Dec;35(12):2822-30
The ribosomal protein S26 regulates p53 activity in response to DNA damage.
Cui D, Li L, Lou H, Sun H, Ngai SM, Shao G, Tang J
Oncogene 2014 Apr 24;33(17):2225-35
Oncogene 2014 Apr 24;33(17):2225-35
Regulation of Actinomycin D induced upregulation of Mdm2 in H1299 cells.
Li L, Cui D, Zheng SJ, Lou H, Tang J
DNA repair 2012 Feb 1;11(2):112-9
DNA repair 2012 Feb 1;11(2):112-9
Defective ribosome assembly in Shwachman-Diamond syndrome.
Wong CC, Traynor D, Basse N, Kay RR, Warren AJ
Blood 2011 Oct 20;118(16):4305-12
Blood 2011 Oct 20;118(16):4305-12
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The RPL11 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RPL11. This antibody recognizes human,mouse,rat antigen. The RPL11 antibody has been validated for the following applications: ELISA, WB analysis.