Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 14424-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14424-1-AP, RRID:AB_2198921
- Product name
- TAX1BP1 antibody
- Antibody type
- Polyclonal
- Description
- TAX1BP1 antibody (Cat. #14424-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity.
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.
A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy.
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Friesen O, Wu W, Stuhldreier F, Sun Y, Berning L, Friedrich A, Mendiburo MJ, Peter C, Wiek C, Hanenberg H, Stefanski A, Stühler K, Stork B
Scientific reports 2021 Jul 5;11(1):13863
Scientific reports 2021 Jul 5;11(1):13863
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Wu W, Wang X, Sun Y, Berleth N, Deitersen J, Schlütermann D, Stuhldreier F, Wallot-Hieke N, José Mendiburo M, Cox J, Peter C, Bergmann AK, Stork B
Autophagy 2021 Dec;17(12):3992-4009
Autophagy 2021 Dec;17(12):3992-4009
Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity.
Hall BS, Dos Santos SJ, Hsieh LT, Manifava M, Ruf MT, Pluschke G, Ktistakis N, Simmonds RE
Autophagy 2021 Aug 23;:1-19
Autophagy 2021 Aug 23;:1-19
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Zhong Z, Qian Z, Zhang X, Chen F, Ni S, Kang Z, Zhang F, Li D, Yu B
Frontiers in pharmacology 2019;10:1530
Frontiers in pharmacology 2019;10:1530
Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.
Zachari M, Gudmundsson SR, Li Z, Manifava M, Cugliandolo F, Shah R, Smith M, Stronge J, Karanasios E, Piunti C, Kishi-Itakura C, Vihinen H, Jokitalo E, Guan JL, Buss F, Smith AM, Walker SA, Eskelinen EL, Ktistakis NT
Developmental cell 2019 Sep 9;50(5):627-643.e5
Developmental cell 2019 Sep 9;50(5):627-643.e5
A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy.
Yang C, Zang W, Tang Z, Ji Y, Xu R, Yang Y, Luo A, Hu B, Zhang Z, Liu Z, Zheng X
Cancer research 2018 Feb 15;78(4):1069-1082
Cancer research 2018 Feb 15;78(4):1069-1082
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR, McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, Diaz-Meco MT, Moscat J, Karin M
Cell 2016 Feb 25;164(5):896-910
Cell 2016 Feb 25;164(5):896-910
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The TAX1BP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TAX1BP1. This antibody recognizes human, mouse antigen. The TAX1BP1 antibody has been validated for the following applications: ELISA, WB analysis.