Antibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 14424-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14424-1-AP, RRID:AB_2198921
- Product name
- TAX1BP1 antibody
- Antibody type
- Polyclonal
- Description
- TAX1BP1 antibody (Cat. #14424-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.
Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway.
Alleviation of monocyte exhaustion by BCG derivative mycolic acid.
TRAM deletion attenuates monocyte exhaustion and alleviates sepsis severity.
Copper-dependent autophagic degradation of GPX4 drives ferroptosis.
Profiling of purified autophagic vesicle degradome in the maturing and aging brain.
PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles.
The long noncoding RNA LTCONS5539 up-regulates the TRAF6-mediated immune responses in miiuy croaker (Miichthys miiuy).
A detrimental role of NLRP6 in host iron metabolism during Salmonella infection.
Neuroprotective effect of alpha-kinase 1 knockdown against cerebral ischemia through inhibition of the NF-κB pathway and neuroinflammation.
Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity.
FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.
A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy.
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Hou S, Zhang J, Jiang X, Yang Y, Shan B, Zhang M, Liu C, Yuan J, Xu D
Molecular cell 2024 Mar 7;84(5):938-954.e8
Molecular cell 2024 Mar 7;84(5):938-954.e8
Protein disulfide isomerase family member 4 promotes triple-negative breast cancer tumorigenesis and radiotherapy resistance through JNK pathway.
Tao J, Xue C, Cao M, Ye J, Sun Y, Chen H, Guan Y, Zhang W, Zhang W, Yao Y
Breast cancer research : BCR 2024 Jan 2;26(1):1
Breast cancer research : BCR 2024 Jan 2;26(1):1
Alleviation of monocyte exhaustion by BCG derivative mycolic acid.
Wu Y, Caldwell B, Wang J, Zhang Y, Li L
iScience 2024 Feb 16;27(2):108978
iScience 2024 Feb 16;27(2):108978
TRAM deletion attenuates monocyte exhaustion and alleviates sepsis severity.
Wang J, Wu Y, Lin R, Zhang Y, Li L
Frontiers in immunology 2023;14:1297329
Frontiers in immunology 2023;14:1297329
Copper-dependent autophagic degradation of GPX4 drives ferroptosis.
Xue Q, Yan D, Chen X, Li X, Kang R, Klionsky DJ, Kroemer G, Chen X, Tang D, Liu J
Autophagy 2023 Jul;19(7):1982-1996
Autophagy 2023 Jul;19(7):1982-1996
Profiling of purified autophagic vesicle degradome in the maturing and aging brain.
Kallergi E, Siva Sankar D, Matera A, Kolaxi A, Paolicelli RC, Dengjel J, Nikoletopoulou V
Neuron 2023 Aug 2;111(15):2329-2347.e7
Neuron 2023 Aug 2;111(15):2329-2347.e7
PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles.
Fan Y, Cheng Z, Mao L, Xu G, Li N, Zhang M, Weng P, Zheng L, Dong X, Hu S, Wang B, Qin X, Jiang X, Chen C, Zhang J, Zou Z
Journal of nanobiotechnology 2022 Mar 19;20(1):149
Journal of nanobiotechnology 2022 Mar 19;20(1):149
The long noncoding RNA LTCONS5539 up-regulates the TRAF6-mediated immune responses in miiuy croaker (Miichthys miiuy).
Pan J, Zheng W, Sun Y, Xu T
Fish & shellfish immunology 2022 Jul;126:263-270
Fish & shellfish immunology 2022 Jul;126:263-270
A detrimental role of NLRP6 in host iron metabolism during Salmonella infection.
Deng Q, Yang S, Sun L, Huang K, Dong K, Zhu Y, Cao Y, Li Y, Wu S, Huang R
Redox biology 2022 Feb;49:102217
Redox biology 2022 Feb;49:102217
Neuroprotective effect of alpha-kinase 1 knockdown against cerebral ischemia through inhibition of the NF-κB pathway and neuroinflammation.
Li JY, Zheng ZX, Liu L, Du O, Yu NW, Zou Y, Seong SY, Du JR
International immunopharmacology 2022 Dec;113(Pt A):109330
International immunopharmacology 2022 Dec;113(Pt A):109330
Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity.
Hall BS, Dos Santos SJ, Hsieh LT, Manifava M, Ruf MT, Pluschke G, Ktistakis N, Simmonds RE
Autophagy 2022 Apr;18(4):841-859
Autophagy 2022 Apr;18(4):841-859
FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.
Schlütermann D, Berleth N, Deitersen J, Wallot-Hieke N, Friesen O, Wu W, Stuhldreier F, Sun Y, Berning L, Friedrich A, Mendiburo MJ, Peter C, Wiek C, Hanenberg H, Stefanski A, Stühler K, Stork B
Scientific reports 2021 Jul 5;11(1):13863
Scientific reports 2021 Jul 5;11(1):13863
TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagy.
Wu W, Wang X, Sun Y, Berleth N, Deitersen J, Schlütermann D, Stuhldreier F, Wallot-Hieke N, José Mendiburo M, Cox J, Peter C, Bergmann AK, Stork B
Autophagy 2021 Dec;17(12):3992-4009
Autophagy 2021 Dec;17(12):3992-4009
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Zhong Z, Qian Z, Zhang X, Chen F, Ni S, Kang Z, Zhang F, Li D, Yu B
Frontiers in pharmacology 2019;10:1530
Frontiers in pharmacology 2019;10:1530
Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform.
Zachari M, Gudmundsson SR, Li Z, Manifava M, Cugliandolo F, Shah R, Smith M, Stronge J, Karanasios E, Piunti C, Kishi-Itakura C, Vihinen H, Jokitalo E, Guan JL, Buss F, Smith AM, Walker SA, Eskelinen EL, Ktistakis NT
Developmental cell 2019 Sep 9;50(5):627-643.e5
Developmental cell 2019 Sep 9;50(5):627-643.e5
A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy.
Yang C, Zang W, Tang Z, Ji Y, Xu R, Yang Y, Luo A, Hu B, Zhang Z, Liu Z, Zheng X
Cancer research 2018 Feb 15;78(4):1069-1082
Cancer research 2018 Feb 15;78(4):1069-1082
NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria.
Zhong Z, Umemura A, Sanchez-Lopez E, Liang S, Shalapour S, Wong J, He F, Boassa D, Perkins G, Ali SR, McGeough MD, Ellisman MH, Seki E, Gustafsson AB, Hoffman HM, Diaz-Meco MT, Moscat J, Karin M
Cell 2016 Feb 25;164(5):896-910
Cell 2016 Feb 25;164(5):896-910
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TAX1BP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TAX1BP1. This antibody recognizes human, mouse antigen. The TAX1BP1 antibody has been validated for the following applications: ELISA, WB analysis.