BS8219

antibody from Bioworld Technology, Inc
Targeting: GDA
Provider product page for BS8219
Western blot
Immunohistochemistry

Antibody data

Product number
BS8219 - Provider product page
Provider
Bioworld Technology, Inc
Product name
GDA polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human GDA.
Description
The assembly of neurotransmitter receptors and associated signal transduction machinery at synaptic sites involves postsynaptic density 95 (PSD-95) and related membrane-associated guanylate kinase (MAGUK) proteins. Cypin, (Cytoplasmic PSD-95 interactor, also designated guanine deaminase and nedasin S), regulates intermediate steps in postsynaptic protein sorting, such as synaptic clustering of MAGUK proteins, and associates with multiple members of the PSD-95 family . Expressed both pre- and post-synaptically, cypin is most prevalent within the cytoplasm of dendritic shafts and in the neck of synaptic spines . In non-neuronal cells, cypin is most highly expressed in the basal membrane of intestinal epithelial cells. Cypin is also highly expressed in kidney, liver, lung, brain, and spleen, with lower levels of expression in placenta, heart, and skeletal muscle . Native cypin may also be expressed as a dimer and a tetramer .
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
GDA protein structure - BS8219 shown in red.